Phosphatidylinositol Binding clathrin Assembly Protein Produkte
(Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
Kategorien
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10\;11)(p13\;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].
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Ausgewählte Phosphatidylinositol Binding clathrin Assembly Protein Kategorien
Phosphatidylinositol Binding clathrin Assembly Protein Antikörper
High quality antibodies with extensive validation data.
Phosphatidylinositol Binding clathrin Assembly Protein ELISA Kits
Reliable ELISA kits for a wide range of species.
Phosphatidylinositol Binding clathrin Assembly Protein Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Phosphatidylinositol Binding clathrin Assembly Protein Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7163230
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN1501903
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validierungen
- (1)
Kat. Nr.
ABIN1385889
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Phosphatidylinositol Binding clathrin Assembly Protein ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958523
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5657760
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Phosphatidylinositol Binding clathrin Assembly Protein Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1315001
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2728884
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7408408
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Phosphatidylinositol Binding clathrin Assembly Protein Produkten
: "Cellular protein profiles altered by PRRSV infection of porcine monocytes-derived dendritic cells." in: Veterinary microbiology, Vol. 228, pp. 134-142, (2019) (PubMed).: "Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice." in: Journal of biomedical science, Vol. 23, Issue 1, pp. 49, (2016) (PubMed).
: "Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's disease." in: BMC neuroscience, Vol. 17, Issue 1, pp. 50, (2016) (PubMed).
: "Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance." in: Nature neuroscience, Vol. 18, Issue 7, pp. 978-87, (2015) (PubMed).
: "Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis." in: PLoS ONE, Vol. 10, Issue 6, pp. e0129776, (2015) (PubMed).
: "Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 150-60, (2014) (PubMed).
: "Distribution and expression of picalm in Alzheimer disease." in: Journal of neuropathology and experimental neurology, Vol. 69, Issue 10, pp. 1071-7, (2010) (PubMed).
Synonyme und alternative Namen zu Phosphatidylinositol Binding clathrin Assembly Protein
leucine aminopeptidase 3 (LAP3), phosphatidylinositol binding clathrin assembly protein (PICALM), phosphatidylinositol binding clathrin assembly protein (Picalm), si:ch211-200p22.4 (si:ch211-200p22.4), CALM, Calm, CLTH, fit-1, fit1, LAP, LAP-3, mKIAA4114, PAP180, PEPSBezeichner auf Proteinebene für Phosphatidylinositol Binding clathrin Assembly Protein
- LAP
- cytosol aminopeptidase
- leucyl aminopeptidase
- peptidase S
- proline aminopeptidase
- prolyl aminopeptidase
- clathrin assembly lymphoid myeloid leukemia protein
- phosphatidylinositol-binding clathrin assembly protein
- clathrin assembly lymphoid myeloid leukemia
- clathrin-assembly lymphoid leukemia protein
- clathrin-assembly lymphoid myeloid leukemia protein
- rCALM
- uncharacterized protein LOC772071
Haben Sie etwas anderes gesucht?
- Phosphatidylinositol Antibody IgG/IgM
- Phosphate-Binding Protein PstS 1
- Phosphate Cytidylyltransferase 1, Choline, beta
- Phosphate Cytidylyltransferase 1, Choline, alpha
- Phosphatase and Tensin Homolog
- Phosphatase and Actin Regulator 4
- Phosphatase and Actin Regulator 3
- Phosducin-Like
- Phosducin
- PHO85
- PHNC2
- PHLPP2
- PHLPP1
- PHLDB3
- PHLDB2
- PHLDB1
- PHLDA3
- PHLDA2
- PHLDA1
- PHKG2
- Phosphatidylinositol Phosphate
- Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta
- Phospho Protein Kinase C
- Phospho-Extracellular Signal-Regulated Kinase
- PHOSPHO1
- PHOSPHO2
- Phosphodiesterase
- Phosphodiesterase I
- Phosphodiesterase II
- phosphofructokinase, Muscle
- Phosphoglucomutase 1
- Phosphoglucomutase 2
- Phosphoglucomutase 3
- Phosphoglucomutase 5
- Phosphoglycerate Kinase
- Phosphoglycerate Mutase
- phosphoglycerate Mutase 1 (Brain)
- Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide
- Phosphoinositide-Specific phospholipase C
- Phospholamban
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