PIK3C2B Produkte
(Phosphatidylinositol-4-Phosphate 3-Kinase, Catalytic Subunit Type 2 beta (PIK3C2B))
Kategorien
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008].
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Ausgewählte PIK3C2B Kategorien
PIK3C2B Antikörper
High quality antibodies with extensive validation data.
PIK3C2B Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PIK3C2B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IHC (p)
Validierungen
- (8)
Kat. Nr.
ABIN1500199
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (4)
Kat. Nr.
ABIN518887
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IHC (p), IF
Validierungen
- (4)
Kat. Nr.
ABIN1500198
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PIK3C2B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315065
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7405546
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2728944
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PIK3C2B Produkten
: "PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets." in: Molecular metabolism, Vol. 5, Issue 7, pp. 459-71, (2016) (PubMed).: "Association of Factor V Secretion with Protein Kinase B Signaling in Platelets from Horses with Atypical Equine Thrombasthenia." in: Journal of veterinary internal medicine, Vol. 29, Issue 5, pp. 1387-94, (2016) (PubMed).
: "Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity." in: The Journal of biological chemistry, Vol. 273, Issue 49, pp. 33082-90, (1999) (PubMed).
Synonyme und alternative Namen zu PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta (Pik3c2b), phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta (PIK3C2B), C2-PI3KBezeichner auf Proteinebene für PIK3C2B
- nuclear cap binding protein subunit 2
- phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta
- phosphoinositide-3-kinase, class 2, beta polypeptide
- PI3K-C2-beta
- PI3K-C2beta
- PTDINS-3-kinase C2 beta
- phosphatidylinositol 3-kinase C2 domain-containing beta polypeptide
- phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
- phosphoinositide 3-kinase-C2-beta
- ptdIns-3-kinase C2 subunit beta
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