PIK3R5 Produkte
(Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
Kategorien
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011].
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Ausgewählte PIK3R5 Kategorien
PIK3R5 Antikörper
High quality antibodies with extensive validation data.
PIK3R5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PIK3R5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Dog, Human, Monkey, Mouse, Rat
Applikation
WB, IHC, IF, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN1500211
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Monkey, Mouse, Rat
Applikation
WB, IHC, IF, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN1500212
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (3)
Kat. Nr.
ABIN655491
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene PIK3R5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315090
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505214
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094632
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PIK3R5 Produkten
: "Genetic Profiles Associated with Chemoresistance in Patient-Derived Xenograft Models of Ovarian Cancer." in: Cancer research and treatment : official journal of Korean Cancer Association, (2018) (PubMed).: "A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia." in: Human mutation, Vol. 33, Issue 2, pp. 351-4, (2012) (PubMed).
: "Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma." in: The Journal of cell biology, Vol. 160, Issue 1, pp. 89-99, (2003) (PubMed).
: "Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2." in: Molecular and cellular biology, Vol. 16, Issue 3, pp. 762-70, (1996) (PubMed).
: "Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin." in: Nature, Vol. 372, Issue 6506, pp. 570-3, (1995) (PubMed).
: "p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest." in: Genes & development, Vol. 8, Issue 1, pp. 9-22, (1994) (PubMed).
Synonyme und alternative Namen zu PIK3R5
phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), phosphoinositide-3-kinase regulatory subunit 5 S homeolog (pik3r5.S), phosphoinositide-3-kinase, regulatory subunit 5 (Pik3r5), phosphoinositide-3-kinase regulatory subunit 5 (Pik3r5), AV230647, F730038I15Rik, FOAP-2, p101, P101, P101-PI3K, RGD1563261Bezeichner auf Proteinebene für PIK3R5
- PI3-kinase regulatory subunit 5
- phosphoinositide-3-kinase, regulatory subunit 5, p101
- PI3-kinase p101 subunit
- phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit
- phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit
- phosphoinositide 3-kinase regulatory subunit 5
- protein FOAP-2
- ptdIns-3-kinase p101
- Phosphoinositide 3-kinase regulatory subunit 5
- IB PI3-kinase p101 subunit
- p101-PI3K
- ptdIns-3-kinase regulatory subunit
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