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PIK3R5 Produkte

(Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))

Kategorien

Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011].

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Ausgewählte PIK3R5 Kategorien

PIK3R5 Antikörper

High quality antibodies with extensive validation data.

PIK3R5 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PIK3R5 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Dog, Human, Monkey, Mouse, Rat
Applikation WB, IHC, IF, IHC (p)
Validierungen
  • (6)
Kat. Nr. ABIN1500211
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Human, Monkey, Mouse, Rat
Applikation WB, IHC, IF, IHC (p)
Validierungen
  • (6)
Kat. Nr. ABIN1500212
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p), FACS
Validierungen
  • (3)
Kat. Nr. ABIN655491
Menge 400 μL
Datenblatt Datenblatt

Empfohlene PIK3R5 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315090
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505214
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3094632
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PIK3R5 Produkten

Li, Kim, Park, Lee, Kim, Lee, Kim, Kim, Kim, Nam: "Genetic Profiles Associated with Chemoresistance in Patient-Derived Xenograft Models of Ovarian Cancer." in: Cancer research and treatment : official journal of Korean Cancer Association, (2018) (PubMed).

Al Tassan, Khalil, Shinwari, Al Sharif, Bavi, Abduljaleel, Abu Dhaim, Magrashi, Bobis, Ahmed, Alahmed, Bohlega: "A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia." in: Human mutation, Vol. 33, Issue 2, pp. 351-4, (2012) (PubMed).

Brock, Schaefer, Reusch, Czupalla, Michalke, Spicher, Schultz, Nürnberg: "Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma." in: The Journal of cell biology, Vol. 160, Issue 1, pp. 89-99, (2003) (PubMed).

Gorospe, Liu, Xu, Chrest, Holbrook: "Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2." in: Molecular and cellular biology, Vol. 16, Issue 3, pp. 762-70, (1996) (PubMed).

Nourse, Firpo, Flanagan, Coats, Polyak, Lee, Massague, Crabtree, Roberts: "Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin." in: Nature, Vol. 372, Issue 6506, pp. 570-3, (1995) (PubMed).

Polyak, Kato, Solomon, Sherr, Massague, Roberts, Koff: "p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest." in: Genes & development, Vol. 8, Issue 1, pp. 9-22, (1994) (PubMed).

Synonyme und alternative Namen zu PIK3R5

phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), phosphoinositide-3-kinase regulatory subunit 5 S homeolog (pik3r5.S), phosphoinositide-3-kinase, regulatory subunit 5 (Pik3r5), phosphoinositide-3-kinase regulatory subunit 5 (Pik3r5), AV230647, F730038I15Rik, FOAP-2, p101, P101, P101-PI3K, RGD1563261

Bezeichner auf Proteinebene für PIK3R5

  • PI3-kinase regulatory subunit 5
  • phosphoinositide-3-kinase, regulatory subunit 5, p101
  • PI3-kinase p101 subunit
  • phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit
  • phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit
  • phosphoinositide 3-kinase regulatory subunit 5
  • protein FOAP-2
  • ptdIns-3-kinase p101
  • Phosphoinositide 3-kinase regulatory subunit 5
  • IB PI3-kinase p101 subunit
  • p101-PI3K
  • ptdIns-3-kinase regulatory subunit
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