PIN1 Produkte
(Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
Kategorien
Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011].
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Ausgewählte PIN1 Kategorien
PIN1 Antikörper
High quality antibodies with extensive validation data.
PIN1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PIN1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PIN1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, FACS, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN652906
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF, FACS
Validierungen
- (9)
Kat. Nr.
ABIN3028920
Menge
0.4 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (4)
Kat. Nr.
ABIN3022930
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PIN1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6974378
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969199
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958454
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PIN1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124343
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN666676
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315108
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PIN1 Produkten
: "Pin1 and secondary hyperparathyroidism of chronic kidney disease: gene polymorphisms and protein levels." in: Renal failure, Vol. 39, Issue 1, pp. 159-165, (2017) (PubMed).: "Pin1 regulates osteoclast fusion through suppression of the master regulator of cell fusion DC-STAMP." in: Journal of cellular physiology, Vol. 229, Issue 12, pp. 2166-74, (2014) (PubMed).
: "Pin1 plays a critical role as a molecular switch in canonical BMP signaling." in: Journal of cellular physiology, Vol. 230, Issue 3, pp. 640-7, (2014) (PubMed).
: "Regulation of the microRNA 200b (miRNA-200b) by transcriptional regulators PEA3 and ELK-1 protein affects expression of Pin1 protein to control anoikis." in: The Journal of biological chemistry, Vol. 288, Issue 45, pp. 32742-52, (2013) (PubMed).
: "The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancer." in: PLoS ONE, Vol. 8, Issue 2, pp. e55355, (2013) (PubMed).
: "Androgen receptor serine 81 mediates Pin1 interaction and activity." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 18, pp. 3415-20, (2013) (PubMed).
: "Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1." in: Cell death and differentiation, Vol. 19, Issue 7, pp. 1152-61, (2012) (PubMed).
: "Pin1 interacts with c-Myb in a phosphorylation-dependent manner and regulates its transactivation activity." in: Biochimica et biophysica acta, Vol. 1783, Issue 6, pp. 1121-8, (2008) (PubMed).
: "Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity." in: Journal of neurochemistry, Vol. 106, Issue 2, pp. 734-45, (2008) (PubMed).
: "Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy." in: The Journal of clinical investigation, Vol. 118, Issue 5, pp. 1877-89, (2008) (PubMed).
Synonyme und alternative Namen zu PIN1
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1), peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (Pin1), peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1), peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog (pin1.S), protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Pin1), peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog (pin1.L), peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (ppiD), peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PITG_11123), peptidyl-prolyl cis-trans isomerase Pin1 (pin1), peptidyl-prolyl cis-trans isomerase Pin1 (LOC103419188), 0610025L01Rik, D9Bwg1161e, DOD, dod, MdPin1, pin1, Pin1, pin1a, pin1b, PPIase pin1, UBL5, ubl5, zgc:73206Bezeichner auf Proteinebene für PIN1
- PPIase Pin1
- peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
- protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
- rotamase Pin1
- protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1
- prolyl isomerase Pin1
- peptidylprolyl cis/trans isomerase, NIMA-interacting 1 a
- peptidyl-prolyl cis-trans isomerase Pin1
- prolyl isomerase Pin1 b
- peptidylprolyl cis/trans isomerase, NIMA-interacting 1 b
- Pin1-type peptidyl-prolyl cis/trans isomerase
- Rotamase Pin1
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