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PKC beta Produkte

(Protein Kinase C, beta (PRKCB))

Kategorien

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Ausgewählte PKC beta Kategorien

PKC beta Antikörper

High quality antibodies with extensive validation data.

PKC beta ELISA Kits

Reliable ELISA kits for a wide range of species.

PKC beta Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PKC beta Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN6146199
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (4)
Kat. Nr. ABIN6146200
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7165698
Menge 100 μg
Datenblatt Datenblatt

Empfohlene PKC beta ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380789
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene PKC beta Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316257
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2729604
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2729603
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PKC beta Produkten

Kuai, Luo, Qu, Ru, Luo, Ding, Xing, Liu, Sun, Li, Li: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." in: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).

Dobrikov, Dobrikova, Gromeier: "Ribosomal RACK1:Protein Kinase C βII Modulates Intramolecular Interactions between Unstructured Regions of Eukaryotic Initiation Factor 4G (eIF4G) That Control eIF4E and eIF3 Binding." in: Molecular and cellular biology, Vol. 38, Issue 19, (2018) (PubMed).

Gan, Wang, Zhao, Wu, Yang, Peng: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." in: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).

Wang, Qin, Deng, Yao: "Different localization and expression of protein kinase C-beta in kidney cortex of diabetic nephropathy mice and its role in telmisartan treatment." in: American journal of translational research, Vol. 7, Issue 6, pp. 1116-25, (2015) (PubMed).

Nakura, Higuchi, Yoshida, Yoshikawa: "PKC? suppresses osteoblastic differentiation." in: Bone, Vol. 48, Issue 3, pp. 476-84, (2011) (PubMed).

Fu, Deng, Zhao, Li, Zhou, Zhang: "Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters." in: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 185-92, (2010) (PubMed).

Losso, Truax, Richard: "trans-resveratrol inhibits hyperglycemia-induced inflammation and connexin downregulation in retinal pigment epithelial cells." in: Journal of agricultural and food chemistry, Vol. 58, Issue 14, pp. 8246-52, (2010) (PubMed).

Zhang, Major, Takanashi, Camp, Nishiya, Peters, Ginsberg, Jian, Randazzo, Schultz, Moon, Ding: "Small-molecule synergist of the Wnt/beta-catenin signaling pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 18, pp. 7444-8, (2007) (PubMed).

Robertson, Kahl, Vose, de Vos, Laughlin, Flynn, Rowland, Cruz, Goldberg, Musib, Darstein, Enas, Kutok, Aster, Neuberg, Savage, LaCasce, Thornton, Slapak, Shipp: "Phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 25, Issue 13, pp. 1741-6, (2007) (PubMed).

Maines, Miralem, Lerner-Marmarosh, Shen, Gibbs: "Human biliverdin reductase, a previously unknown activator of protein kinase C betaII." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8110-22, (2007) (PubMed).

Synonyme und alternative Namen zu PKC beta

protein kinase C beta (PRKCB), protein kinase C, beta (Prkcb), protein kinase C, beta b (prkcbb), protein kinase C, beta a (prkcba), A130082F03Rik, PKC, PKC-B, PKC-beta, PKC-Beta, Pkc53E, PKCB, Pkcb, Prkcb, PRKCB1, Prkcb1, prkcb1, prkcb1l, PRKCB2, Prkcb2, PRKCB_tv2, zgc:63591, zgc:64063

Bezeichner auf Proteinebene für PKC beta

  • PKC-B
  • protein kinase C beta type
  • protein kinase C, beta 1 polypeptide
  • protein kinase C beta-II
  • protein kinase C, beta 1
  • PKC-beta
  • protein kinase C beta I
  • protein kinase C beta II
  • protein kinase C beta 1
  • protein kinase C, beta
  • protein kinase C beta 2
  • protein kinase C, beta 1, like
  • protein kinase C, beta a
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