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PKC theta Produkte

(Protein Kinase C, theta (PRKCQ))

Kategorien

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008].

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Ausgewählte PKC theta Kategorien

PKC theta Antikörper

High quality antibodies with extensive validation data.

PKC theta ELISA Kits

Reliable ELISA kits for a wide range of species.

PKC theta Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PKC theta Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, IF, ICC
Validierungen
  • (5)
Kat. Nr. ABIN6256401
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IP, IHC (f)
Validierungen
  • (5)
  • (4)
Kat. Nr. ABIN967739
Menge 150 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (3)
Kat. Nr. ABIN7443020
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PKC theta ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962224
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1116786
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1116787
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PKC theta Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316274
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5509109
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7415938
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PKC theta Produkten

van Rees, Lago, Cox, Tomasik, Rustogi, Weigelt, Ozcan, Cooper, Drexhage, Leweke, Bahn: "Evidence of microglial activation following exposure to serum from first-onset drug-naïve schizophrenia patients." in: Brain, behavior, and immunity, Vol. 67, pp. 364-373, (2018) (PubMed).

Marino, Hinds, Potter, Ondrus, Onion, Dowling, McLoughlin, Sanchez, Hill: "Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation." in: BMC cell biology, Vol. 14, pp. 39, (2013) (PubMed).

Van Kolen, Slegers: "Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells." in: The FEBS journal, Vol. 273, Issue 8, pp. 1843-54, (2006) (PubMed).

Xu, Chaudhary, Olland, Wolfrom, Czerwinski, Malakian, Lin, Stahl, Joseph-McCarthy, Benander, Fitz, Greco, Somers, Mosyak: "Catalytic domain crystal structure of protein kinase C-theta (PKCtheta)." in: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 50401-9, (2004) (PubMed).

Thebault, Ochoa-Garay: "Characterization of TCR-induced phosphorylation of PKCtheta in primary murine lymphocytes." in: Molecular immunology, Vol. 40, Issue 13, pp. 931-42, (2004) (PubMed).

Sun, Mao, Rao et al.: "Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in ..." in: Blood, Vol. 103, Issue 3, pp. 948-54, (2004) (PubMed).

Burchfield, Lennard, Narasimhan, Hughes, Wasinger, Corthals, Okuda, Kondoh, Biden, Schmitz-Peiffer: "Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta." in: The Journal of biological chemistry, Vol. 279, Issue 18, pp. 18623-32, (2004) (PubMed).

Zhang, Anastasiadis, Liu, Thompson, Fields: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).

Carrasco, Merida: "Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes." in: Molecular biology of the cell, Vol. 15, Issue 6, pp. 2932-42, (2004) (PubMed).

Zhang, Keane, Zhu, Sharma, Rozengurt, Strieter, Dubinett, Huang: "Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28315-9, (2004) (PubMed).

Synonyme und alternative Namen zu PKC theta

protein kinase C theta (PRKCQ), protein kinase C eta (PRKCH), protein kinase C, theta (Prkcq), protein kinase C theta (Prkcq), A130035A12Rik, AW494342, nPKC-theta, PKC-0, PKC-theta, Pkcq, PKCtheta, PRKCT

Bezeichner auf Proteinebene für PKC theta

  • protein kinase C theta type
  • PKC theta
  • nPKC-theta
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