PKC zeta Produkte
(Protein Kinase C, zeta (PRKCZ))
Kategorien
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte PKC zeta Kategorien
PKC zeta Antikörper
High quality antibodies with extensive validation data.
PKC zeta ELISA Kits
Reliable ELISA kits for a wide range of species.
PKC zeta Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PKC zeta Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (5)
Kat. Nr.
ABIN6264247
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (5)
Kat. Nr.
ABIN6256558
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, RNAi
Validierungen
- (4)
Kat. Nr.
ABIN562397
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PKC zeta ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969724
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969723
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958931
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PKC zeta Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124655
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316280
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316282
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PKC zeta Produkten
: "PKCζ in prostate cancer cells represses the recruitment and M2 polarization of macrophages in the prostate cancer microenvironment." in: Tumour biology, Vol. 39, Issue 6, pp. 1010428317701442, (2017) (PubMed).: "Metabolic maintenance of cell asymmetry following division in activated T lymphocytes." in: Nature, Vol. 532, Issue 7599, pp. 389-93, (2016) (PubMed).
: "Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota." in: Cancer research, Vol. 68, Issue 18, pp. 7403-8, (2008) (PubMed).
: "Regulation of TNF-alpha-activated PKC-zeta signaling by the human biliverdin reductase: identification of activating and inhibitory domains of the reductase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 3949-62, (2007) (PubMed).
: "Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms." in: The Journal of biological chemistry, Vol. 281, Issue 44, pp. 33773-88, (2006) (PubMed).
: "Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions." in: Journal of biochemistry, Vol. 133, Issue 1, pp. 1-7, (2003) (PubMed).
: "Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes." in: European journal of biochemistry / FEBS, Vol. 216, Issue 2, pp. 597-606, (1993) (PubMed).
: "The cDNA sequence encoding human protein kinase C-zeta." in: Gene, Vol. 132, Issue 2, pp. 305-6, (1993) (PubMed).
Synonyme und alternative Namen zu PKC zeta
protein kinase C zeta L homeolog (prkcz.L), protein kinase C zeta (PRKCZ), protein kinase C zeta (prkcz), protein kinase C, zeta (PRKCZ), protein kinase C, zeta (Prkcz), protein kinase C zeta (Prkcz), protein kinase C, zeta (prkcz), 14-3-3-zetaisoform, AI098070, aPKCzeta, C80388, pkc-zeta, PKC-ZETA, pkc2, PKC2, Pkcz, pkcz, PKCzeta, PRKCZ, prkcz-A, r14-3-3, R74924, si:ch211-150o23.4, TPKC, zetaPKCBezeichner auf Proteinebene für PKC zeta
- protein kinase C, zeta
- protein kinase c type Z
- protein kinase C zeta type
- protein kinase C zeta type-like
- nPKC-zeta
- atypical protein kinase C
- protein kinase C zeta subspecies
- 14 - 3 - 3 - zeta isoform
- atypical protein kinase C zeta
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