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PLA2G4A Produkte

(Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008].

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Ausgewählte PLA2G4A Kategorien

PLA2G4A Antikörper

High quality antibodies with extensive validation data.

PLA2G4A ELISA Kits

Reliable ELISA kits for a wide range of species.

PLA2G4A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PLA2G4A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7438268
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN3187717
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7437737
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PLA2G4A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958564
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969300
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969299
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PLA2G4A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315289
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7394447
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7394444
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PLA2G4A Produkten

Meng, Du, Li, Gao, Song, Lu, Tu, Jiang, Guo: "The synergistic mechanism of total saponins and flavonoids in Notoginseng-Safflower pair against myocardial ischemia uncovered by an integrated metabolomics strategy." in: Biomedicine & pharmacotherapy, Vol. 130, pp. 110574, (2020) (PubMed).

Zhang, Wu, Gan, Yu, Wang, Wang, Wang, Wang: "Reduced group IVA phospholipase A2 expression is associated with unfavorable outcome for patients with gastric cancer." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 1, pp. 454, (2013) (PubMed).

Onyimba, Coronado, Garton, Kim, Bucek, Bedja, Gabrielson, Guilarte, Fairweather: "The innate immune response to coxsackievirus B3 predicts progression to cardiovascular disease and heart failure in male mice." in: Biology of sex differences, Vol. 2, pp. 2, (2011) (PubMed).

Gubern, Barceló-Torns, Barneda, López, Masgrau, Picatoste, Chalfant, Balsinde, Balboa, Claro: "JNK and ceramide kinase govern the biogenesis of lipid droplets through activation of group IVA phospholipase A2." in: The Journal of biological chemistry, Vol. 284, Issue 47, pp. 32359-69, (2009) (PubMed).

Synonyme und alternative Namen zu PLA2G4A

phospholipase A2 group IVA (PLA2G4A), phospholipase A2 group IVA (Pla2g4a), phospholipase A2 group IVA L homeolog (pla2g4a.L), phospholipase A2, group IVA (cytosolic, calcium-dependent) (Pla2g4a), phospholipase A2, group IVAb (cytosolic, calcium-dependent) (pla2g4ab), cPLA2, CPLA2, cPLA2-alpha, cPLA2alpha, PLA2, Pla2c, PLA2G1B, PLA2G4, Pla2g4, pla2g4, PLA2G4A, pla2g4a, si:dkey-97o5.1

Bezeichner auf Proteinebene für PLA2G4A

  • cPLA2
  • calcium-dependent phospholipid-binding protein
  • cytosolic phospholipase A2
  • lysophospholipase
  • phosphatidylcholine 2-acylhydrolase
  • phospholipase A2 group IVA
  • phospholipase A2 cytosolic
  • Phospholipase A2 group IVA
  • phospholipase A2, group IB (pancreas)
  • Cytosolic phospholipase A2 (CPLA2)
  • Type IV PLA2
  • cPLA2-alpha
  • cytosolic PLA2
  • phospholipase A2, group 4
  • phospholipase A2, group IVA (cytosolic, calcium-dependent)
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