PLAUR Produkte
(Plasminogen Activator, Urokinase Receptor (PLAUR))
Kategorien
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008].
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Ausgewählte PLAUR Kategorien
PLAUR Antikörper
High quality antibodies with extensive validation data.
PLAUR ELISA Kits
Reliable ELISA kits for a wide range of species.
PLAUR Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PLAUR Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7431179
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, FACS, IF (cc)
Validierungen
- (5)
Kat. Nr.
ABIN675443
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, FACS
Validierungen
- (4)
Kat. Nr.
ABIN7193215
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PLAUR ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (5)
- (1)
Kat. Nr.
ABIN6958616
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6958617
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969366
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PLAUR Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (5)
Kat. Nr.
ABIN7275406
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7275402
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275407
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PLAUR Produkten
: "uPAR isoform 2 forms a dimer and induces severe kidney disease in mice." in: The Journal of clinical investigation, Vol. 130, (2019) (PubMed).: "Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease." in: Nature medicine, Vol. 23, Issue 1, pp. 100-106, (2017) (PubMed).
: "Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor - β1 (TGF-β1) and potential effects on migration and invasion." in: BMC cancer, Vol. 17, Issue 1, pp. 350, (2017) (PubMed).
: "Urokinase-type Plasminogen Activator (uPA) Binding to the uPA Receptor (uPAR) Promotes Axonal Regeneration in the Central Nervous System." in: The Journal of biological chemistry, Vol. 292, Issue 7, pp. 2741-2753, (2017) (PubMed).
: "Clinical value of soluble urokinase-type plasminogen activator receptor in the diagnosis, prognosis, and therapeutic guidance of sepsis." in: The American journal of emergency medicine, Vol. 34, Issue 3, pp. 375-80, (2016) (PubMed).
: "Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. ..." in: Nature communications, Vol. 7, pp. 11626, (2016) (PubMed).
: "A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease." in: Kidney international, Vol. 87, Issue 3, pp. 564-74, (2015) (PubMed).
: "Tumour microenvironments induce expression of urokinase plasminogen activator receptor (uPAR) and concomitant activation of gelatinolytic enzymes." in: PLoS ONE, Vol. 9, Issue 8, pp. e105929, (2015) (PubMed).
: "uPAR and cathepsin B-mediated compartmentalization of JNK regulates the migration of glioma-initiating cells." in: Stem cell research, Vol. 12, Issue 3, pp. 716-29, (2014) (PubMed).
: "Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures." in: Biophysical journal, Vol. 107, Issue 9, pp. 2101-11, (2014) (PubMed).
Synonyme und alternative Namen zu PLAUR
plasminogen activator, urokinase receptor (Plaur), plasminogen activator, urokinase receptor (PLAUR), Cd87, CD87, Par, PLAUR, Plaur3, u-PAR, U-PAR, uPAR, UPAR, uPAR-2, uPAR-3, URKRBezeichner auf Proteinebene für PLAUR
- urokinase plasminogen activator receptor
- urokinase plasminogen activator surface receptor
- urokinase-type plasminogen activator receptor
- monocyte activation antigen Mo3
- u-plasminogen activator receptor form 2
- urokinase-type plasminogen activator (uPA) receptor
- U-PAR
- plasminogen activator urokinase receptor 3
- urinary plasminogen activator receptor 2
- urinary plasminogen activator receptor 3
- uPAR
- plasminogen activator, urokinase receptor
Haben Sie etwas anderes gesucht?
- PLAU
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- Platelet Factor 3
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- PLAT
- Plastin 3
- Plasmolipin
- Plasmodium Vivax MSP1
- Plasmodium Falciparum Histidine Rich Protein 2
- Plasmodium Falciparum
- Plasminogen Activator
- Plasmin/antiplasmin Complex
- Plasmin
- Plasmepsin-1
- PLAP
- Plakophilin 4
- Plakophilin 3
- Plakophilin 2
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