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Pleiotrophin Produkte

(Pleiotrophin (PTN))
Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation (By similarity).

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Ausgewählte Pleiotrophin Kategorien

Pleiotrophin Antikörper

High quality antibodies with extensive validation data.

Pleiotrophin ELISA Kits

Reliable ELISA kits for a wide range of species.

Pleiotrophin Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Pleiotrophin Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (8)
  • (5)
Kat. Nr. ABIN562528
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN7218552
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (3)
Kat. Nr. ABIN7433426
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Pleiotrophin ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN6574270
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958661
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962237
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Pleiotrophin Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275498
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Human Cells
Validierungen
  • (1)
Kat. Nr. ABIN7320789
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316796
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Pleiotrophin Produkten

He, Boulant, Stanifer, Guo, Nießen, Chen, Felix, Bergmann, Strobel, Schimmack: "The link between menin and pleiotrophin in the tumor biology of pancreatic neuroendocrine neoplasms." in: Cancer science, Vol. 113, Issue 5, pp. 1575-1586, (2022) (PubMed).

Wu, Xu, Bao, Gao, Chen, Zhang, Chen, Hong, Xue, Jiang, Liu, Huang, Sun, Fu, Li, Cui: "Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin." in: The Journal of biological chemistry, Vol. 298, Issue 10, pp. 102443, (2022) (PubMed).

Hauser, Kaminski, Syring, Holdenrieder, Dieckmann, Muller, Ellinger: "Evaluation of Serum Biomarkers (FGF-2, HGF, MIF and PTN) in Patients With Testicular Germ Cell Cancer." in: In vivo (Athens, Greece), Vol. 33, Issue 6, pp. 1935-1940, (2020) (PubMed).

Nikolakopoulou, Montagne, Kisler, Dai, Wang, Huuskonen, Sagare, Lazic, Sweeney, Kong, Wang, Owens, Lawson, Xie, Zhao, Zlokovic: "Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss." in: Nature neuroscience, Vol. 22, Issue 7, pp. 1089-1098, (2019) (PubMed).

Wang, LeBlanc, Chen, Chen, Ji, Brewer, Tian, Spring, Webster, Li: "Pathogenic role and therapeutic potential of pleiotrophin in mouse models of ocular vascular disease." in: Angiogenesis, Vol. 20, Issue 4, pp. 479-492, (2018) (PubMed).

Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." in: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).

Terkawi, Nishimura, Furuoka, Nishikawa: "Depletion of Phagocytic Cells during Nonlethal Plasmodium yoelii Infection Causes Severe Malaria Characterized by Acute Renal Failure in Mice." in: Infection and immunity, Vol. 84, Issue 3, pp. 845-55, (2016) (PubMed).

Zhu, Bai, Yu, Pan, Jin, Song, Xu, Yao, Huang, Tao, Li, Zhao: "The effects of pleiotrophin in proliferative diabetic retinopathy." in: PLoS ONE, Vol. 10, Issue 1, pp. e0115523, (2015) (PubMed).

Koutsioumpa, Polytarchou, Courty, Zhang, Kieffer, Mikelis, Skandalis, Hellman, Iliopoulos, Papadimitriou: "Interplay between ?v?3 integrin and nucleolin regulates human endothelial and glioma cell migration." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 343-54, (2013) (PubMed).

Kaspiris, Mikelis, Heroult, Khaldi, Grivas, Kouvaras, Dangas, Vasiliadis, Lioté, Courty, Papadimitriou: "Expression of the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in the serum, cartilage and subchondral bone of patients with osteoarthritis." in: Joint, bone, spine : revue du rhumatisme, Vol. 80, Issue 4, pp. 407-13, (2013) (PubMed).

Synonyme und alternative Namen zu Pleiotrophin

pleiotrophin (ptn), pleiotrophin (PTN), pleiotrophin L homeolog (ptn.L), pleiotrophin (Ptn), harp, HARP, HB-GAM, HBBM, HBBN, HBGF-8, hbgf8, HBGF8, hbnf, HBNF, Hbnf, negf1, NEGF1, OSF, OSF-1, Osf-1, Osf1, ptn, PTN, PTN-A, X-PTF, zgc:111787, zHBNF

Bezeichner auf Proteinebene für Pleiotrophin

  • heparin-binding neurite-promoting factor
  • pleiotrophin
  • pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
  • Pleiotrophin
  • HB-GAM
  • HBBM
  • HBGF-8
  • HBNF-1
  • OSF-1
  • heparin affin regulatory protein
  • heparin binding growth factor 8
  • heparin-binding brain mitogen
  • heparin-binding growth factor 8
  • heparin-binding growth-associated molecule
  • heparin-binding neurite outgrowth-promoting factor 1
  • neurite growth-promoting factor 1
  • osteoblast-specific factor 1
  • PTF-beta-1
  • X-PTF-beta1
  • pleiotrophic factor-beta-1
  • pleiotrophin-A
  • heparin-binding neutrophic factor
  • p18
  • heparin affin regulatory peptide
  • heparin-binding neurite promoting factor
  • heparin-binding neurotorphic factor
  • osteoblastic cell factor
  • Pleiotrophin (Heparine binding factor, Hbnf, in the mouse)
  • heparin binding factor
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