PMEPA1 Produkte
(Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
Kategorien
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
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Ausgewählte PMEPA1 Kategorien
PMEPA1 Antikörper
High quality antibodies with extensive validation data.
PMEPA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PMEPA1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PMEPA1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
IHC, StM
Validierungen
- (5)
Kat. Nr.
ABIN6940417
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (8)
- (2)
Kat. Nr.
ABIN566055
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, StM
Validierungen
- (3)
Kat. Nr.
ABIN6940418
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PMEPA1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1163040
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1163041
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PMEPA1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315510
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3117192
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3129250
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PMEPA1 Produkten
: "Mutation or loss of p53 differentially modifies TGF? action in ovarian cancer." in: PLoS ONE, Vol. 9, Issue 2, pp. e89553, (2014) (PubMed).: "TGF-? induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer." in: Genes & cancer, Vol. 5, Issue 9-10, pp. 320-36, (2014) (PubMed).
: "Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma." in: Cancer research, Vol. 73, Issue 13, pp. 3888-901, (2013) (PubMed).
: "TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways." in: Carcinogenesis, Vol. 34, Issue 8, pp. 1764-72, (2013) (PubMed).
: "High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone." in: Cellular & molecular biology letters, Vol. 12, Issue 3, pp. 370-7, (2012) (PubMed).
: "TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling." in: Molecular cell, Vol. 37, Issue 1, pp. 123-34, (2010) (PubMed).
: "Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer." in: Cancer research, Vol. 70, Issue 15, pp. 6377-83, (2010) (PubMed).
: "A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 43, pp. 28988-95, (2008) (PubMed).
Synonyme und alternative Namen zu PMEPA1
prostate transmembrane protein, androgen induced 1 (Pmepa1), prostate transmembrane protein, androgen induced 1 (PMEPA1), prostate transmembrane protein, androgen induced 1 (pmepa1), prostate transmembrane protein, androgen induced 1 L homeolog (pmepa1.L), 2210418I02Rik, AW455466, Erg1.2, N4wbp4, PMEPA1, STAG1, Stag1, Tmepai, TMEPAI, tmepai, zgc:92731Bezeichner auf Proteinebene für PMEPA1
- transmembrane prostate androgen-induced protein
- transmembrane, prostate androgen induced RNA
- prostate transmembrane protein, androgen induced 1
- solid tumor-associated 1 protein
- NEDD4 WW domain-binding protein 4
- Nedd4 WW binding protein 4
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