PNKP Produkte
(Polynucleotide Kinase 3'-Phosphatase (PNKP))
Kategorien
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte PNKP Kategorien
PNKP Antikörper
High quality antibodies with extensive validation data.
PNKP ELISA Kits
Reliable ELISA kits for a wide range of species.
PNKP Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PNKP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (1)
- (8)
Kat. Nr.
ABIN6145836
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN7262583
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (5)
Kat. Nr.
ABIN564910
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene PNKP ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1123845
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1123846
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PNKP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315552
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315550
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3086075
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PNKP Produkten
: "MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas." in: Cancer discovery, Vol. 9, Issue 4, pp. 526-545, (2019) (PubMed).: "Mechanism for recycling tRNAs on stalled ribosomes." in: Nature structural & molecular biology, Vol. 26, Issue 5, pp. 343-349, (2019) (PubMed).
: "Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription." in: eLife, Vol. 8, (2019) (PubMed).
: "In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer. ..." in: Nature communications, Vol. 9, Issue 1, pp. 3501, (2018) (PubMed).
: "Quantitative Label-Free Phosphoproteomics Reveals Differentially Regulated Protein Phosphorylation Involved in West Nile Virus-Induced Host Inflammatory Response." in: Journal of proteome research, Vol. 14, Issue 12, pp. 5157-68, (2016) (PubMed).
: "Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3667-79, (2015) (PubMed).
: "Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability." in: The EMBO journal, Vol. 34, Issue 19, pp. 2465-80, (2015) (PubMed).
: "Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage." in: Nucleic acids research, Vol. 39, Issue 21, pp. 9224-37, (2011) (PubMed).
: "Spectroscopic studies of DNA and ATP binding to human polynucleotide kinase: evidence for a ternary complex." in: Biochemistry, Vol. 42, Issue 41, pp. 12077-84, (2003) (PubMed).
: "Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining." in: The EMBO journal, Vol. 21, Issue 11, pp. 2827-32, (2002) (PubMed).
Synonyme und alternative Namen zu PNKP
polynucleotide kinase 3'-phosphatase (PNKP), polynucleotide kinase 3'-phosphatase (Pnkp), polynucleotide kinase 3'-phosphatase (Tc00.1047053507017.50), polynucleotide kinase 3'-phosphatase (Tc00.1047053505807.190), polynucleotide kinase 3'-phosphatase (Tb927.6.1580), polynucleotide kinase 3'-phosphatase (BBOV_IV000690), polynucleotide kinase 3'-phosphatase (CC1G_05202), hypothetical protein (PGTG_20262), hypothetical protein (PGTG_18987), polynucleotide kinase 3'-phosphatase (pnkp.S), polynucleotide kinase 3'-phosphatase (pnkp), polynucleotide kinase 3'- phosphatase (Pnkp), 21.m03011, 1810009G08Rik, EIEE10, MCSZ, PNK, Tb06.28P18.320Bezeichner auf Proteinebene für PNKP
- DNA 5'-kinase/3'-phosphatase
- Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP)
- bifunctional polynucleotide phosphatase/kinase
- polynucleotide kinase 3'-phosphatase
- polynucleotide kinase-3'-phosphatase
Sie sind hier:
