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POFUT1 Produkte

(Protein O-Fucosyltransferase 1 (POFUT1))

Kategorien

This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Ausgewählte POFUT1 Kategorien

POFUT1 Antikörper

High quality antibodies with extensive validation data.

POFUT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

POFUT1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene POFUT1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7444553
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN525219
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (2)
Kat. Nr. ABIN7444556
Menge 100 μL
Datenblatt Datenblatt

Empfohlene POFUT1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969730
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1134573
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1134574
Menge 96 tests
Datenblatt Datenblatt

Empfohlene POFUT1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315608
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315606
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN2131215
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren POFUT1 Produkten

Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Takeuchi, Wong, Schneider, Freeze, Takeuchi, Berardinelli, Ito, Lee, Nelson, Haltiwanger: "Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features." in: Glycobiology, Vol. 28, Issue 5, pp. 276-283, (2018) (PubMed).

Annani-Akollor, Wang, Fan, Liu, Padhiar, Zhang: "Downregulated protein O-fucosyl transferase 1 (Pofut1) expression exerts antiproliferative and antiadhesive effects on hepatocytes by inhibiting Notch signalling." in: Biomedicine & pharmacotherapy, Vol. 68, Issue 6, pp. 785-90, (2014) (PubMed).

Stahl, Uemura, Ge, Shi, Tashima, Stanley: "Roles of Pofut1 and O-fucose in mammalian Notch signaling." in: The Journal of biological chemistry, Vol. 283, Issue 20, pp. 13638-51, (2008) (PubMed).

Loriol, Dupuy, Rampal, Dlugosz, Haltiwanger, Maftah, Germot: "Molecular evolution of protein O-fucosyltransferase genes and splice variants." in: Glycobiology, Vol. 16, Issue 8, pp. 736-47, (2006) (PubMed).

Shi, Stanley: "Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 9, pp. 5234-9, (2003) (PubMed).

Wang, Shao, Shi, Harris, Spellman, Stanley, Haltiwanger: "Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 40338-45, (2001) (PubMed).

Synonyme und alternative Namen zu POFUT1

protein O-fucosyltransferase 1 (POFUT1), protein O-fucosyltransferase 1 (pofut1), protein O-fucosyltransferase 1 (Pofut1), DDD2, fut12, FUT12, Fut12, mKIAA0180, o-fuc-t, O-Fuc-T, o-fuct-1, O-FucT-1, o-fut, O-FUT, OFUCT1, pofut1, zgc:110472

Bezeichner auf Proteinebene für POFUT1

  • GDP-fucose protein O-fucosyltransferase 1
  • putative protein-O-fucosyltransferase
  • O-FucT-1
  • peptide-O-fucosyltransferase 1
  • protein-O-fucosyltransferase 1
  • protein-O-fucosyltransferase
  • protein O-fucosyltransferase 1
  • o-fucosyltransferase protein
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