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POLB Produkte

(Polymerase (DNA Directed), beta (POLB))

Kategorien

The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011].

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Ausgewählte POLB Kategorien

POLB Antikörper

High quality antibodies with extensive validation data.

POLB ELISA Kits

Reliable ELISA kits for a wide range of species.

POLB Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene POLB Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN3022385
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN1327635
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6264332
Menge 100 μL
Datenblatt Datenblatt

Empfohlene POLB ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958686
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1381085
Menge 96 tests
Datenblatt Datenblatt

Empfohlene POLB Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124515
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124514
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315620
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren POLB Produkten

Sykora, Kanno, Akbari, Kulikowicz, Baptiste, Leandro, Lu, Tian, May, Becker, Croteau, Wilson, Sobol, Yasui, Bohr: "DNA polymerase beta participates in mitochondrial DNA repair." in: Molecular and cellular biology, (2017) (PubMed).

Dutto, Sukhanova, Tillhon, Cazzalini, Stivala, Scovassi, Lavrik, Prosperi: "p21CDKN1A Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146031, (2016) (PubMed).

Preet, Siddharth, Satapathy, Das, Nayak, Das, Wyatt, Kundu: "Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade." in: Biochemical pharmacology, Vol. 105, pp. 23-33, (2016) (PubMed).

Siddharth, Nayak, Nayak, Das, Kundu: "ABT-888 and quinacrine induced apoptosis in metastatic breast cancer stem cells by inhibiting base excision repair via adenomatous polyposis coli." in: DNA repair, Vol. 45, pp. 44-55, (2016) (PubMed).

Xu, Zhang, Zhang, Meng, Zhang, Jiang, Xu, Van Meter, Seluanov, Gorbunova, Mao: "SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 2, pp. 269-76, (2015) (PubMed).

Quiñones, Thapar, Yu, Fang, Sobol, Demple: "Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 28, pp. 8602-7, (2015) (PubMed).

Li, Li, Yu, Zhang, Wang, Jia: "miR-3940-5p associated with genetic damage in workers exposed to hexavalent chromium." in: Toxicology letters, Vol. 229, Issue 1, pp. 319-26, (2014) (PubMed).

Swain, Rao: "Age-dependent decline of DNA base excision repair activity in rat cortical neurons." in: Mechanisms of ageing and development, Vol. 133, Issue 4, pp. 186-94, (2012) (PubMed).

Huang, Qu, Zhang, Venderova, Haque, Rousseaux, Slack, Woulfe, Park: "The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death." in: Nature cell biology, Vol. 12, Issue 6, pp. 563-71, (2010) (PubMed).

Asagoshi, Liu, Masaoka, Lan, Prasad, Horton, Brown, Wang, Bdour, Sobol, Taylor, Yasui, Wilson: "DNA polymerase beta-dependent long patch base excision repair in living cells." in: DNA repair, Vol. 9, Issue 2, pp. 109-19, (2010) (PubMed).

Synonyme und alternative Namen zu POLB

polymerase (DNA directed), beta (polb), DNA polymerase beta (POLB), DNA polymerase X family protein (polB), polymerase (DNA directed), beta S homeolog (polb.S), polymerase (DNA directed), beta (Polb), DNA polymerase beta (Polb), A430088C08Rik, DDBDRAFT_0186152, DDBDRAFT_0215784, DDBDRAFT_0232376, DDB_0186152, DDB_0215784, DDB_0232376, POLB, wu:fa97a05, zgc:109924

Bezeichner auf Proteinebene für POLB

  • DNA-directed DNA polymerase beta
  • DNA polymerase beta
  • polymerase (DNA directed), beta
  • DNA polymerase beta-like
  • DNA pol beta
  • DNA polymerase beta subunit
  • mutant DNA polymerase beta
  • Pol beta
  • polymerase-beta
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