POLK Produkte
(Polymerase (DNA Directed) kappa (POLK))
Kategorien
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).[supplied by OMIM, Jan 2010].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte POLK Kategorien
POLK Antikörper
High quality antibodies with extensive validation data.
POLK Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene POLK Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p), RNAi
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN565606
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN949322
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IF
Validierungen
- (2)
Kat. Nr.
ABIN7261966
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene POLK ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6206770
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene POLK Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315652
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124513
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094746
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren POLK Produkten
: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).: "Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication." in: Molecular and cellular biology, Vol. 35, Issue 4, pp. 699-715, (2015) (PubMed).
: "Crystal structure of the catalytic core of human DNA polymerase kappa." in: Structure (London, England : 1993), Vol. 12, Issue 8, pp. 1395-404, (2004) (PubMed).
: "Translesion synthesis past 2'-deoxyxanthosine, a nitric oxide-derived DNA adduct, by mammalian DNA polymerases." in: Journal of molecular biology, Vol. 344, Issue 3, pp. 665-74, (2004) (PubMed).
: "A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair." in: Genes & development, Vol. 17, Issue 22, pp. 2777-85, (2003) (PubMed).
: "Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene." in: The Journal of biological chemistry, Vol. 275, Issue 50, pp. 39678-84, (2001) (PubMed).
: "Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa." in: Genes & development, Vol. 14, Issue 13, pp. 1589-94, (2000) (PubMed).
: "The metabolism of oleic, linoleic and linolenic acids by sheep with reference to their effects on methane production." in: The British journal of nutrition, Vol. 20, Issue 2, pp. 349-62 (PubMed).
Synonyme und alternative Namen zu POLK
DNA polymerase kappa (POLK), DNA polymerase kappa (Polk), polymerase (DNA directed) kappa (polk), DNA polymerase kappa (Tb11.01.0080), DNA polymerase kappa (Tb11.01.0010), DNA polymerase kappa (Tb11.01.0020), DNA polymerase kappa (Tb11.01.0030), DNA polymerase kappa (Tb11.01.0040), DNA polymerase kappa (Tb11.01.0050), DNA polymerase kappa (Tb11.12.0001), DNA polymerase kappa (Tb11.12.0002), DNA polymerase kappa (Tb11.12.0003), polymerase (DNA directed), kappa (Polk), polymerase (DNA directed) kappa L homeolog (polk.L), DNA polymerase kappa (polk-1), DINB1, Dinb1, DINP, POLK, POLQ, si:ch211-254o18.3Bezeichner auf Proteinebene für POLK
- DNA polymerase kappa
- DNA-directed DNA polymerase kappa
- polymerase (DNA directed) kappa
- DNA polymerase kappa-like
- DINB protein
- DINP
- DNA damage-inducible protein b
- DinB homolog 1
Sie sind hier:
