POLK Proteine
(Polymerase (DNA Directed) kappa (POLK))
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).[supplied by OMIM, Jan 2010].
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custom-made
POLK
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
POLK
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
POLK
Spezies: Human
Wirt: Wheat germ
Recombinant
ELISA, WB, AP, AA
1 image
POLK
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by SDS-PAGE
ELISA, WB
1 image
custom-made
POLK
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
POLK
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
POLK
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aktuelle Publikationen für unsere POLK Proteine
: "Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene." in: The Journal of biological chemistry, Vol. 275, Issue 50, pp. 39678-84, (2001) (PubMed).: "Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa." in: Genes & development, Vol. 14, Issue 13, pp. 1589-94, (2000) (PubMed).
: "The metabolism of oleic, linoleic and linolenic acids by sheep with reference to their effects on methane production." in: The British journal of nutrition, Vol. 20, Issue 2, pp. 349-62 (PubMed).
Aliase für POLK Proteine
DNA polymerase kappa (POLK) ProteineDNA polymerase kappa (Polk) Proteine
polymerase (DNA directed) kappa (polk) Proteine
DNA polymerase kappa (Tb11.01.0080) Proteine
DNA polymerase kappa (Tb11.01.0010) Proteine
DNA polymerase kappa (Tb11.01.0020) Proteine
DNA polymerase kappa (Tb11.01.0030) Proteine
DNA polymerase kappa (Tb11.01.0040) Proteine
DNA polymerase kappa (Tb11.01.0050) Proteine
DNA polymerase kappa (Tb11.12.0001) Proteine
DNA polymerase kappa (Tb11.12.0002) Proteine
DNA polymerase kappa (Tb11.12.0003) Proteine
polymerase (DNA directed), kappa (Polk) Proteine
polymerase (DNA directed) kappa L homeolog (polk.L) Proteine
DNA polymerase kappa (polk-1) Proteine
DINB1 Proteine
Dinb1 Proteine
DINP Proteine
POLK Proteine
POLQ Proteine
si:ch211-254o18.3 Proteine
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