POLR2A/RPB1 Produkte
(RNA Polymerase II Subunit RPB1 (POLR2A))
Kategorien
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008].
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Ausgewählte POLR2A/RPB1 Kategorien
POLR2A/RPB1 Antikörper
High quality antibodies with extensive validation data.
POLR2A/RPB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
POLR2A/RPB1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene POLR2A/RPB1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7265278
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IP, ChIP
Validierungen
- (5)
Kat. Nr.
ABIN6145914
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IP
Validierungen
- (5)
Kat. Nr.
ABIN3022933
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene POLR2A/RPB1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380131
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene POLR2A/RPB1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315666
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Chinese Hamster
Source
Yeast
Validierungen
Kat. Nr.
ABIN1609970
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren POLR2A/RPB1 Produkten
: "Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes." in: eLife, Vol. 7, (2019) (PubMed).: "Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome." in: Nucleic acids research, Vol. 47, Issue 1, pp. 122-133, (2019) (PubMed).
: "Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination." in: Molecular cell, Vol. 74, Issue 1, pp. 158-172.e9, (2019) (PubMed).
: "Targeting CDK9 and MCL-1 by a new CDK9/p-TEFb inhibitor with and without 5-fluorouracil in esophageal adenocarcinoma." in: Therapeutic advances in medical oncology, Vol. 11, pp. 1758835919864850, (2019) (PubMed).
: "ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop." in: Molecular cell, (2019) (PubMed).
: "Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma." in: Oncotarget, Vol. 8, Issue 17, pp. 28696-28710, (2017) (PubMed).
: "PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia." in: Oncotarget, Vol. 7, Issue 6, pp. 6379-97, (2016) (PubMed).
: "Rpb4/7 facilitates RNA polymerase II CTD dephosphorylation." in: Nucleic acids research, Vol. 42, Issue 22, pp. 13674-88, (2015) (PubMed).
: "Function and control of RNA polymerase II C-terminal domain phosphorylation in vertebrate transcription and RNA processing." in: Molecular and cellular biology, Vol. 34, Issue 13, pp. 2488-98, (2014) (PubMed).
: "Identification of novel inhibitors of human immunodeficiency virus type 1 replication by in silico screening targeting cyclin T1/Tat interaction." in: Antimicrobial agents and chemotherapy, Vol. 57, Issue 3, pp. 1323-31, (2013) (PubMed).
Synonyme und alternative Namen zu POLR2A/RPB1
DNA-directed RNA polymerase II largest subunit (NCU02103), DNA-directed RNA polymerase II largest subunit (BBOV_I003360), DNA-directed RNA polymerase II subunit RPB1 (EDI_169920), DNA-directed RNA polymerase II subunit RPB1 (CMU_000800), RNA polymerase II large subunit Rpb1 (SJAG_01713), DNA-directed RNA polymerase II subunit RPB1 (MGYG_01527), RNA polymerase II subunit A (POLR2A), DNA-directed RNA polymerase II largest subunit (TP03_0185), DNA-directed RNA polymerase II largest subunit (EBI_22514), DNA-directed RNA polymerase II largest subunit, putative (CGB_E5020W), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa (POLR2A), RNA polymerase II subunit A (polr2a), polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), RNA polymerase II subunit A (Polr2a), 19.m02399, 220kDa, hRPB220, hsRPB1, NCU02103.1, POLR2, POLR2A, POLRA, Rpb1, RPB1, RPBh1, RpIILS, RPO2, Rpo2-1, RPOL2Bezeichner auf Proteinebene für POLR2A/RPB1
- DNA-directed RNA polymerase II subunit RPB1
- polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- 220 kDa DNA-directed RNA polymerase polypeptide A
- DNA-directed RNA polymerase II largest subunit
- RNA polymerase II polypeptide A
- DNA-directed RNA polymerase II A
- DNA-directed RNA polymerase II subunit A
- DNA-directed RNA polymerase III largest subunit
- RNA polymerase II 1
- RNA polymerase II subunit B1
- Polymerase (RNA II (DNA directed), large polypeptide
- DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit
- RNA-directed RNA polymerase II subunit RPB1
- polymerase (RNA) II (DNA directed) polypeptide A (220kD)
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