Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 Produkte
(Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2))
Kategorien
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010].
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Ausgewählte Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 Kategorien
Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 Antikörper
High quality antibodies with extensive validation data.
Empfohlene Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN2752370
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA
Validierungen
Kat. Nr.
ABIN6389105
Menge
100 μL
Datenblatt
Datenblatt
Synonyme und alternative Namen zu Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2
poly(A) binding protein nuclear 1 (PABPN1), poly(A) binding protein cytoplasmic 1 pseudogene 2 (PABPC1P2), OPMD, PAB2, PABII, PABP-2, PABP2, PABP4, PABPCP2, PABPCP4Bezeichner auf Proteinebene für Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2
- poly(A) binding protein 2
- poly(A) binding protein II
- polyadenylate-binding protein 2
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