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PON2 Produkte

(Paraoxonase 2 (PON2))
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Ausgewählte PON2 Kategorien

PON2 Antikörper

High quality antibodies with extensive validation data.

PON2 ELISA Kits

Reliable ELISA kits for a wide range of species.

PON2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PON2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, IHC, ICC, IP
Validierungen
  • (7)
Kat. Nr. ABIN7440995
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN651946
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN2855759
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PON2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969140
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958392
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958393
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PON2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315744
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7397240
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7407646
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PON2 Produkten

Devarajan, Su, Grijalva, Yalamanchi, Yalamanchi, Gao, Trost, Nwokedi, Farias-Eisner, Farias-Eisner, Fogelman, Reddy: "Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer." in: Cell death & disease, Vol. 9, Issue 3, pp. 392, (2019) (PubMed).

Schwarzer, Fu, Morita, Whitt, Neely, Li, Machen: "Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone." in: The Journal of biological chemistry, Vol. 290, Issue 11, pp. 7247-58, (2015) (PubMed).

Parsanejad, Bourquard, Qu, Zhang, Huang, Rousseaux, Aleyasin, Irrcher, Callaghan, Vaillant, Kim, Slack, Mak, Reddy, Figeys, Park: "DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress." in: PLoS ONE, Vol. 9, Issue 9, pp. e106601, (2014) (PubMed).

Devarajan, Bourquard, Hama, Navab, Grijalva, Morvardi, Clarke, Vergnes, Reue, Teiber, Reddy: "Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis." in: Antioxidants & redox signaling, Vol. 14, Issue 3, pp. 341-51, (2011) (PubMed).

Shin: "Paraoxonase gene polymorphism in south-western Korean population." in: Journal of Korean medical science, Vol. 24, Issue 4, pp. 561-6, (2009) (PubMed).

Rochu, Chabrière, Masson: "Human paraoxonase: a promising approach for pre-treatment and therapy of organophosphorus poisoning." in: Toxicology, Vol. 233, Issue 1-3, pp. 47-59, (2007) (PubMed).

Mackness, Mackness: "Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?" in: Free radical biology & medicine, Vol. 37, Issue 9, pp. 1317-23, (2004) (PubMed).

Reddy, Wadleigh, Grijalva, Ng, Hama, Gangopadhyay, Shih, Lusis, Navab, Fogelman: "Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 21, Issue 4, pp. 542-7, (2001) (PubMed).

Synonyme und alternative Namen zu PON2

serum paraoxonase/arylesterase 2 (LOC100303695), paraoxonase 2 (PON2), paraoxonase 2 L homeolog (pon2.L), serum paraoxonase/arylesterase 2 (BDBG_00600), Serum paraoxonase/arylesterase 2 (pon2), paraoxonase 2 (Pon2), 6330405I24Rik, AI481612, MGC53915, pon1, PON2, pon2

Bezeichner auf Proteinebene für PON2

  • A-esterase 2
  • Aromatic esterase 2
  • PON 2
  • Serum aryldialkylphosphatase 2
  • Serum paraoxonase/arylesterase 2
  • paraoxonase 2
  • celiac disease 2
  • serum paraoxonase/arylesterase 2-like
  • serum paraoxonase/arylesterase 2
  • aromatic esterase 2
  • paraoxonase nirs
  • serum aryldialkylphosphatase 2
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