POT1 Produkte
(Protection of Telomeres 1 (POT1))
Kategorien
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte POT1 Kategorien
POT1 Antikörper
High quality antibodies with extensive validation data.
POT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
POT1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene POT1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7164998
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN565204
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN5663924
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene POT1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958904
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4972163
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5658187
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene POT1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315766
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN2729370
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7409542
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren POT1 Produkten
: "Telomere protein RAP1 levels are affected by cellular aging and oxidative stress." in: Biomedical reports, Vol. 5, Issue 2, pp. 181-187, (2016) (PubMed).: "An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity." in: PLoS ONE, Vol. 11, Issue 5, pp. e0156378, (2016) (PubMed).
: "Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis." in: Frontiers in oncology, Vol. 5, pp. 257, (2015) (PubMed).
: "Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression." in: Aging cell, Vol. 14, Issue 3, pp. 391-9, (2015) (PubMed).
: "Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells." in: Oncotarget, Vol. 6, Issue 35, pp. 38079-92, (2015) (PubMed).
: "The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs." in: Biochimie, Vol. 115, pp. 17-27, (2015) (PubMed).
: "T-oligo as an anticancer agent in colorectal cancer." in: Biochemical and biophysical research communications, Vol. 446, Issue 2, pp. 596-601, (2014) (PubMed).
: "POT1 loss-of-function variants predispose to familial melanoma. ..." in: Nature genetics, Vol. 46, Issue 5, pp. 478-81, (2014) (PubMed).
: "Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response." in: Nucleic acids research, Vol. 41, Issue 2, pp. 900-11, (2013) (PubMed).
: "Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus." in: Oncogene, Vol. 32, Issue 49, pp. 5522-30, (2013) (PubMed).
Synonyme und alternative Namen zu POT1
protection of telomeres 1 (POT1), protection of telomeres 1 L homeolog (pot1.L), protection of telomeres 1A (Pot1a), protection of telomeres 1 (Pot1), 1500031H18Rik, AI851169, DKFZp469P1825, HPOT1, POT1, pot1, Pot1, Pot1aBezeichner auf Proteinebene für POT1
- POT1-like telomere end-binding protein
- protection of telomeres 1 homolog
- protection of telomeres protein 1
- POT1 protection of telomeres 1 homolog
- cPot1
- single-strand telomeric DNA-binding protein
- POT1 protection of telomeres 1 homolog (S. pombe)
- protection of telomeres 1
- protection of telomeres 1 homolog (S. pombe)
- protection of telomeres protein 1-like
- mPot1
- protection of telomeres 1A
Haben Sie etwas anderes gesucht?
- Porin
- PORCN
- Porcine Coronavirus
- PORB
- porB
- PORA
- POR1
- POPDC3
- POPDC2
- POP7
- POP5
- POP3
- POP1
- PON3
- PON2
- PON1
- POMZP3
- POMT2
- POMT1
- POMP
- Potassium Channel KAT3
- Potassium Channel Subfamily K Member 13
- Potassium Channel Tetramerisation Domain Containing 16
- Potassium Channel, Subfamily K, Member 5
- Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2
- Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 5
- POTEA
- POTEB
- POTEB2
- POTEC
- POTED
- POTEE
- POTEF
- POTEG
- POTEH
- POTEI
- POTEJ
- POTEM
- Potential Haloacid Dehalogenase-Like Hydrolase Similar To S. Cerevisiae UTR4 (YEL038W)
- POU Class 3 Homeobox 1
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