PPP2R1A Produkte
(Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))
Kategorien
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
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Ausgewählte PPP2R1A Kategorien
PPP2R1A Antikörper
High quality antibodies with extensive validation data.
PPP2R1A ELISA Kits
Reliable ELISA kits for a wide range of species.
PPP2R1A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PPP2R1A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, IP, IHC (p), ICC
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN2855322
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, PLA
Validierungen
- (3)
Kat. Nr.
ABIN519115
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Drosophila melanogaster, Human, Monkey, Mouse, Rat
Applikation
WB, IF, FACS
Validierungen
- (3)
Kat. Nr.
ABIN354403
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PPP2R1A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971299
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6231881
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PPP2R1A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1316014
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124672
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2729487
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PPP2R1A Produkten
: "PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo." in: Cells, Vol. 9, Issue 1, (2020) (PubMed).: "Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 29, Issue 11, pp. 1424-1432, (2016) (PubMed).
: "PR65A phosphorylation regulates PP2A complex signaling." in: PLoS ONE, Vol. 9, Issue 1, pp. e85000, (2014) (PubMed).
: "Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma." in: Science (New York, N.Y.), Vol. 330, Issue 6001, pp. 228-31, (2010) (PubMed).
: "Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells." in: Nature cell biology, Vol. 12, Issue 9, pp. 886-93, (2010) (PubMed).
: "Protein phosphatase 2A subunit gene haplotypes and proliferative breast disease modify breast cancer risk." in: Cancer, Vol. 116, Issue 1, pp. 8-19, (2010) (PubMed).
: "Hypoxia-activated Smad3-specific dephosphorylation by PP2A." in: The Journal of biological chemistry, Vol. 285, Issue 6, pp. 3740-9, (2010) (PubMed).
: "HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 6, pp. 2622-7, (2010) (PubMed).
: "A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair." in: Neoplasia (New York, N.Y.), Vol. 11, Issue 10, pp. 1012-21, (2009) (PubMed).
: "Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation." in: The Journal of biological chemistry, Vol. 282, Issue 12, pp. 9117-26, (2007) (PubMed).
Synonyme und alternative Namen zu PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), protein phosphatase 2 scaffold subunit A alpha (Ppp2r1a), protein phosphatase 2 regulatory subunit A, alpha L homeolog (ppp2r1a.L), protein phosphatase 2 regulatory subunit A, alpha (ppp2r1a), protein phosphatase 2, regulatory subunit A, beta a (ppp2r1ba), serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (LOC583227), protein phosphatase 2, regulatory subunit A, alpha isoform (Ppp2r1a), protein phosphatase 2, regulatory subunit A, alpha (PPP2R1A), protein phosphatase 2, regulatory subunit A, alpha (Ppp2r1a), protein phosphatase 2 regulatory subunit A, alpha S homeolog (ppp2r1a.S), 6330556D22Rik, PP2A, PP2A-Aalpha, pp2a-aalpha, PP2AAALPHA, pp2aaalpha, ppp2r1a, ppp2r1a-a, ppp2r1a-b, PR65, PR65A, pr65a, wu:fa02h04, zgc:56296Bezeichner auf Proteinebene für PPP2R1A
- PP2A subunit A isoform PR65-alpha
- PP2A subunit A isoform R1-alpha
- medium tumor antigen-associated 61 KDA protein
- protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
- serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform
- serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
- alpha isoform of regulatory subunit A, protein phosphatase 2
- protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform
- protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform
- protein phosphatase 2A 65 kDa regulatory subunit, alpha isoform
- protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
- medium tumor antigen-associated 61 kDa protein
- protein phosphatase 2, regulatory subunit A, alpha
- GLEAN_12508
- serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like
- protein phosphatase PP2A
- serine/threonine protein phosphatase A subunit type 2A
- protein phosphatase 2 regulatory subunit A, alpha S homeolog
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