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PPP2R2B Produkte

(Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Kategorien

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 66-78 copies in cases of SCA12. [provided by RefSeq, Jul 2008].

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Ausgewählte PPP2R2B Kategorien

PPP2R2B Antikörper

High quality antibodies with extensive validation data.

PPP2R2B Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PPP2R2B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (4)
Kat. Nr. ABIN519118
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7169246
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p), FACS
Validierungen
  • (3)
Kat. Nr. ABIN652541
Menge 400 μL
Datenblatt Datenblatt

Empfohlene PPP2R2B ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6231900
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PPP2R2B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316024
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316026
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316028
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PPP2R2B Produkten

Takashina, Kinoshita, Kikuchi, Shimizu, Sakakibara-Konishi, Oizumi, Nishimura, Dosaka-Akita: "Combined inhibition of EZH2 and histone deacetylases as a potential epigenetic therapy for non-small-cell lung cancer cells." in: Cancer science, Vol. 107, Issue 7, pp. 955-62, (2016) (PubMed).

Synonyme und alternative Namen zu PPP2R2B

protein phosphatase 2 regulatory subunit Bbeta (PPP2R2B), protein phosphatase 2, regulatory subunit B, beta (Ppp2r2b), protein phosphatase 2 regulatory subunit B, beta L homeolog (ppp2r2b.L), protein phosphatase 2 regulatory subunit B, beta (ppp2r2b), protein phosphatase 2, regulatory subunit B, beta b (ppp2r2bb), protein phosphatase 2 regulatory subunit Bbeta (Ppp2r2b), 2900026H06Rik, 6330404L05Rik, B55BETA, E130009M08Rik, PP2A, PP2A-PR55B, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, ppp2r2b, PPP2R2B, ppp2r2b-a, ppp2r2c, Pppr2b2, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12, zgc:101861

Bezeichner auf Proteinebene für PPP2R2B

  • PP2A subunit B isoform B55-beta
  • PP2A subunit B isoform PR55-beta
  • PP2A subunit B isoform R2-beta
  • PP2A, subunit B, B-beta isoform
  • protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
  • protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform
  • serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, beta isoform
  • serine/threonine protein phosphatase 2A, neuronal isoform
  • serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
  • BRbeta B-regulatory subunit of protein phosphatase 2A
  • PP2A subunit B isoform BRB
  • PP2A subunit B isoform beta
  • PP2A, subunit B, B55-beta isoform
  • PP2A, subunit B, BRB isoform
  • PP2A, subunit B, PR55-beta isoform
  • PP2A, subunit B, R2-beta isoform
  • phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
  • protein phosphatase 2A 55 kDa regulatory subunit, beta isoform
  • beta isoform of regulatory subunit B55, protein phosphatase 2
  • protein phosphatase-2A subunit-beta
  • protein phosphatase 2, regulatory subunit B, beta
  • serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like
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