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PRG2 Produkte

(Bone Marrow Proteoglycan (PRG2))
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

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Ausgewählte PRG2 Kategorien

PRG2 Antikörper

High quality antibodies with extensive validation data.

PRG2 ELISA Kits

Reliable ELISA kits for a wide range of species.

PRG2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PRG2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN3016204
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (2)
Kat. Nr. ABIN6264418
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN651919
Menge 400 μL
Datenblatt Datenblatt

Empfohlene PRG2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965181
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975292
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975668
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PRG2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316187
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Human Cells
Validierungen
Kat. Nr. ABIN4370675
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Human Cells
Validierungen
Kat. Nr. ABIN7318206
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PRG2 Produkten

Singh, Chand, Banerjee, Agarwal, Raizada, Roy, Sopori: "Acetylcholinesterase Inhibitor Pyridostigmine Bromide Attenuates Gut Pathology and Bacterial Dysbiosis in a Murine Model of Ulcerative Colitis." in: Digestive diseases and sciences, Vol. 65, Issue 1, pp. 141-149, (2020) (PubMed).

Roy, Ehrbar, Bohorova, Bohorov, Kim, Pauly, Whaley, Rong, Torres-Velez, Vitetta, Didier, Doyle-Meyers, Zeitlin, Mantis: "Rescue of rhesus macaques from the lethality of aerosolized ricin toxin." in: JCI insight, Vol. 4, Issue 1, (2019) (PubMed).

Hashimoto, Kursewicz, Fayne, Nanda, Shah, Nattkemper, Yokozeki, Yosipovitch: "Pathophysiological mechanisms of itch in bullous pemphigoid." in: Journal of the American Academy of Dermatology, (2019) (PubMed).

Hashimoto, Kursewicz, Fayne, Nanda, Shah, Nattkemper, Yokozeki, Yosipovitch: "Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages." in: The Journal of investigative dermatology, (2019) (PubMed).

Ziemka-Nalecz, Janowska, Strojek, Jaworska, Zalewska, Frontczak-Baniewicz, Sypecka: "Impact of neonatal hypoxia-ischaemia on oligodendrocyte survival, maturation and myelinating potential." in: Journal of cellular and molecular medicine, Vol. 22, Issue 1, pp. 207-222, (2018) (PubMed).

Costa, Trivellato, Rebech, Oliveira Dos Santos Maciel, Melo, Luvizotto, de Lima: "Eosinophilic inflammation in lymph nodes of dogs with visceral leishmaniasis." in: Parasite immunology, Vol. 40, Issue 8, pp. e12567, (2018) (PubMed).

Gormley, Ona, Kapidzic, Garrido-Gomez, Zdravkovic, Fisher: "Preeclampsia: novel insights from global RNA profiling of trophoblast subpopulations." in: American journal of obstetrics and gynecology, Vol. 217, Issue 2, pp. 200.e1-200.e17, (2017) (PubMed).

Bleyer, Curths, Dahlmann, Wichmann, Bauer, Moritz, Braun, Knauf, Kaup, Gruber-Dujardin: "Morphology and staining behavior of neutrophilic and eosinophilic granulocytes of the common marmoset (Callithrix jacchus)." in: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, (2016) (PubMed).

Vanheel, Vicario, Vanuytsel, Van Oudenhove, Martinez, Keita, Pardon, Santos, Söderholm, Tack, Farré: "Impaired duodenal mucosal integrity and low-grade inflammation in functional dyspepsia." in: Gut, Vol. 63, Issue 2, pp. 262-71, (2014) (PubMed).

Synonyme und alternative Namen zu PRG2

proteoglycan 2, bone marrow (Prg2), proteoglycan 2 (Prg2), proteoglycan 2, pro eosinophil major basic protein (PRG2), BMPG, MBP, MBP1, mMBP, mMBP-1

Bezeichner auf Proteinebene für PRG2

  • BMPG
  • bone marrow proteoglycan
  • major basic protein 1
  • eosinophil major basic protein
  • bone-marrow proteoglycan
  • eosinophil granule major basic protein
  • natural killer cell activator
  • proteoglycan 2 preproprotein
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