PRKAB1 Produkte
(Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
Kategorien
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008].
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Ausgewählte PRKAB1 Kategorien
PRKAB1 Antikörper
High quality antibodies with extensive validation data.
PRKAB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PRKAB1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PRKAB1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7269654
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS
Validierungen
- (4)
Kat. Nr.
ABIN683068
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (4)
Kat. Nr.
ABIN737901
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PRKAB1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969728
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969727
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958933
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PRKAB1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124659
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316211
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7280002
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PRKAB1 Produkten
: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).: "Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer." in: Molecular cancer, Vol. 13, pp. 49, (2014) (PubMed).
: "The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor." in: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 30107-19, (2007) (PubMed).
: "C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism." in: The Journal of biological chemistry, Vol. 279, Issue 5, pp. 3817-27, (2004) (PubMed).
: "AMP-activated protein kinase plays a role in the control of food intake." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12005-8, (2004) (PubMed).
: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." in: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).
: "Posttranslational modifications of the 5'-AMP-activated protein kinase beta1 subunit." in: The Journal of biological chemistry, Vol. 272, Issue 39, pp. 24475-9, (1997) (PubMed).
: "Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 82, Issue 1, pp. 219-25, (1997) (PubMed).
: "Isoform-specific purification and substrate specificity of the 5'-AMP-activated protein kinase." in: The Journal of biological chemistry, Vol. 271, Issue 45, pp. 28445-50, (1996) (PubMed).
: "Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro." in: The Journal of biological chemistry, Vol. 271, Issue 17, pp. 10282-90, (1996) (PubMed).
Synonyme und alternative Namen zu PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1 (PRKAB1), protein kinase, AMP-activated, beta 1 non-catalytic subunit (Prkab1), protein kinase AMP-activated non-catalytic subunit beta 1 (Prkab1), protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog (prkab1.S), protein kinase, AMP-activated, beta 1 non-catalytic subunit (prkab1), protein kinase, AMP-activated, beta 1 non-catalytic subunit, b (prkab1b), protein kinase, AMP-activated, beta 1 non-catalytic subunit, a (prkab1a), 1300015D22Rik, AMPK, AU021155, E430008F22, HAMPKb, MGC82489, prkab1, wu:fk93d05, wu:fw87e09, zgc:56652, zgc:76975, zgc:92228Bezeichner auf Proteinebene für PRKAB1
- 5'-AMP-activated protein kinase beta-1 subunit
- 5'-AMP-activated protein kinase subunit beta-1
- AMP-activated protein kinase beta subunit
- AMPK beta -1 chain
- AMPK beta 1
- AMPK subunit beta-1
- AMPKb
- protein kinase, AMP-activated, noncatalytic, beta-1
- 5'-AMP-activated protein kinase 40 kDa subunit
- 5'-AMP-activated protein kinase, beta subunit
- 5-AMP-activated protein kinase beta subunit
- AMPK beta-1 chain
- 5'AMP-activated protein kinase beta-1 non-catalytic subunit
- protein kinase, AMP-activated, beta 1 non-catalytic subunit
- AMP-activated protein kinase beta 1 non-catalytic subunit
- AMPK-activated protein kinase beta-1 subunit
- protein kinase, AMP-activated, beta 1 non-catalytic subunit, b
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