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PRKACA Produkte

(Protein Kinase A, alpha (PRKACA))

Kategorien

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Ausgewählte PRKACA Kategorien

PRKACA Antikörper

High quality antibodies with extensive validation data.

PRKACA ELISA Kits

Reliable ELISA kits for a wide range of species.

PRKACA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PRKACA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p), IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN2855997
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7146598
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (3)
Kat. Nr. ABIN6264236
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PRKACA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965372
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965371
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965370
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PRKACA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1316219
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316221
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316223
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PRKACA Produkten

Garcia-Alvarez, Lu, Yap, Wong, Thevathasan, Lim, Ji, Tan, Mancuso, Tang, Poon, Augustine, Fivaz: "STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs." in: Molecular biology of the cell, Vol. 26, Issue 6, pp. 1141-59, (2015) (PubMed).

Wang, Zhang, Liang, Zhang, Xu, Zhang, Fuji, Mu, Li, Jiang, Ju, Wang: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).

Chen, Tiong, Tsai, Liao, Yang, Youn, Mai, Chang: "Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency." in: Brain structure & function, (2014) (PubMed).

Brunyanszki, Olah, Coletta, Szczesny, Szabo: "Regulation of mitochondrial poly(ADP-Ribose) polymerase activation by the β-adrenoceptor/cAMP/protein kinase A axis during oxidative stress." in: Molecular pharmacology, Vol. 86, Issue 4, pp. 450-62, (2014) (PubMed).

Beuschlein, Fassnacht, Assié, Calebiro, Stratakis, Osswald, Ronchi, Wieland, Sbiera, Faucz, Schaak, Schmittfull, Schwarzmayr, Barreau, Vezzosi, Rizk-Rabin, Zabel, Szarek, Salpea, Forlino, Vetro et al.: "Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome. ..." in: The New England journal of medicine, Vol. 370, Issue 11, pp. 1019-28, (2014) (PubMed).

Loilome, Yooyuen, Namwat, Sithithaworn, Puapairoj, Kano, Noguchi, Miwa, Yongvanit: "PRKAR1A overexpression is associated with increased ECPKA autoantibody in liver fluke-associated cholangiocarcinoma: application for assessment of the risk group." in: Tumour biology, Vol. 33, Issue 6, pp. 2289-98, (2012) (PubMed).

Zhu, Wang, Kontrogianni-Konstantopoulos, Konstantopoulos: "Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases." in: Cell death and differentiation, Vol. 17, Issue 8, pp. 1325-34, (2010) (PubMed).

Barnitz, Wan, Tripuraneni, Bolton, Lenardo: "Protein kinase A phosphorylation activates Vpr-induced cell cycle arrest during human immunodeficiency virus type 1 infection." in: Journal of virology, Vol. 84, Issue 13, pp. 6410-24, (2010) (PubMed).

Adachi, Kano, Saido, Murata: "Visual screening and analysis for kinase-regulated membrane trafficking pathways that are involved in extensive beta-amyloid secretion." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 14, Issue 3, pp. 355-69, (2009) (PubMed).

Enns, Morton, Mangalindan, McKnight, Schwartz, Kaeberlein, Kennedy, Rabinovitch, Ladiges: "Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A." in: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 64, Issue 12, pp. 1221-31, (2009) (PubMed).

Synonyme und alternative Namen zu PRKACA

protein kinase cAMP-activated catalytic subunit alpha (PRKACA), protein kinase cAMP-activated catalytic subunit alpha (Prkaca), protein kinase, cAMP dependent, catalytic, alpha (Prkaca), cAMP-dependent protein kinase catalytic subunit (kin-1), protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a (prkacaa), Calpha, Cs-PKA, PKA, PKACA, Pkaca, PKCA1, PKCD, zgc:158799

Bezeichner auf Proteinebene für PRKACA

  • PKA C-alpha
  • cAMP-dependent protein kinase catalytic subunit alpha
  • protein kinase A catalytic subunit
  • cAMP-dependent protein kinase catalytic subunit C alpha
  • protein kinase A
  • protein kinase, cAMP-dependent, catalytic, alpha
  • C-alpha subunit
  • sperm cAMP-dependent protein kinase catalytic subunit
  • protein kinase A alpha
  • prkaca
  • PKA catalytic subunit alpha
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