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PRKAG1 Produkte

(Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))

Kategorien

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Ausgewählte PRKAG1 Kategorien

PRKAG1 Antikörper

High quality antibodies with extensive validation data.

PRKAG1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PRKAG1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, ICC, FACS
Validierungen
  • (2)
  • (7)
Kat. Nr. ABIN1724932
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7439723
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7263301
Menge 200 μL
Datenblatt Datenblatt

Empfohlene PRKAG1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN5853248
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316233
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2131292
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PRKAG1 Produkten

Zaha, Young: "AMP-activated protein kinase regulation and biological actions in the heart." in: Circulation research, Vol. 111, Issue 6, pp. 800-14, (2012) (PubMed).

Oliveira, Zhang, Solis, Isackson, Bellahcene, Yavari, Pinter, Davies, Ge, Ashrafian, Walker, Carling, Watkins, Casadei, Redwood: "AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes." in: Circulation research, Vol. 110, Issue 9, pp. 1192-201, (2012) (PubMed).

Lin, Kiihl, Suhail, Liu, Chou, Kuang, Lu, Khor, Lin, Bader, Irizarry, Boeke: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." in: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).

Greer, Oskoui, Banko, Maniar, Gygi, Gygi, Brunet: "The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor." in: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 30107-19, (2007) (PubMed).

Minokoshi, Alquier, Furukawa, Kim, Lee, Xue, Mu, Foufelle, Ferré, Birnbaum, Stuck, Kahn: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." in: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).

Hamilton, Stapleton, ODonnell, Kung, Dalal, Kemp, Witters: "An activating mutation in the gamma1 subunit of the AMP-activated protein kinase." in: FEBS letters, Vol. 500, Issue 3, pp. 163-8, (2001) (PubMed).

Synonyme und alternative Namen zu PRKAG1

protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog (prkag1.S), protein kinase, AMP-activated, gamma 1 non-catalytic subunit (prkag1), protein kinase AMP-activated non-catalytic subunit gamma 1 (PRKAG1), protein kinase AMP-activated non-catalytic subunit gamma 1 (Prkag1), protein kinase, AMP-activated, gamma 1 non-catalytic subunit (Prkag1), AA571379, AMPKG, BB036179, MGC68503, Prkaac, Prkga1, wu:fa94d09, wu:fd12h04, zgc:63896

Bezeichner auf Proteinebene für PRKAG1

  • protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • 5'-AMP-activated protein kinase subunit gamma-1
  • AMPK-activated protein kinase gamma-1 subunit
  • AMP-activated protein kinase, noncatalytic gamma-1 subunit
  • 5'-AMP-activated protein kinase subunit gamma-1-like
  • 5'-AMP-activated protein kinase, gamma-1 subunit
  • AMPK gamma-1 chain
  • AMPK gamma1
  • AMPK subunit gamma-1
  • AMPKg
  • Protein kinase AMP-activated gamma
  • 38 kDa subunit
  • 5'-AMP-activated protein kinase gamma-1 subunit
  • AMP-activated protein kinase subunit gamma 1 (non-catalytic subunit)
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