PRKAR2A Produkte
(Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))
Kategorien
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq, Jul 2008].
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Ausgewählte PRKAR2A Kategorien
PRKAR2A Antikörper
High quality antibodies with extensive validation data.
PRKAR2A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PRKAR2A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN562376
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7146620
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (4)
Kat. Nr.
ABIN1513416
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PRKAR2A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316249
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316251
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN5623689
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PRKAR2A Produkten
: "The inner and outer compartments of mitochondria are sites of distinct cAMP/PKA signaling dynamics." in: The Journal of cell biology, Vol. 202, Issue 3, pp. 453-62, (2013) (PubMed).: "Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein C." in: BMC cell biology, Vol. 12, pp. 18, (2011) (PubMed).
: "Endosome-to-Golgi transport is regulated by protein kinase A type II alpha." in: The Journal of biological chemistry, Vol. 278, Issue 3, pp. 1991-7, (2003) (PubMed).
: "Human myometrial quiescence and activation during gestation and parturition involve dramatic changes in expression and activity of particulate type II (RII alpha) protein kinase A holoenzyme." in: The Journal of clinical endocrinology and metabolism, Vol. 88, Issue 5, pp. 2194-205, (2003) (PubMed).
: "Protein kinase A associates with cystic fibrosis transmembrane conductance regulator via an interaction with ezrin." in: The Journal of biological chemistry, Vol. 275, Issue 19, pp. 14360-6, (2000) (PubMed).
Synonyme und alternative Namen zu PRKAR2A
protein kinase cAMP-dependent type II regulatory subunit alpha (PRKAR2A), protein kinase, cAMP-dependent, regulatory, type II, alpha, B (prkar2ab), protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A), protein kinase, cAMP dependent regulatory, type II alpha (Prkar2a), protein kinase cAMP-dependent type 2 regulatory subunit alpha (Prkar2a), protein kinase cAMP-dependent type II regulatory subunit alpha (Prkar2a), 1110061A24Rik, AI317181, AI836829, PKR2, PRKAR2, prkar2a, PRKAR2A, RII(alpha), zgc:85886Bezeichner auf Proteinebene für PRKAR2A
- cAMP-dependent protein kinase regulatory subunit RII alpha
- cAMP-dependent protein kinase type II-alpha regulatory subunit
- protein kinase A, RII-alpha subunit
- cAMP-dependent protein kinase, regulatory subunit alpha 2
- protein kinase, cAMP-dependent, regulatory, type II, alpha
- cAMP-dependent protein kinase type II-alpha regulatory subunit-like
- protein kinase cAMP-dependent regulatory type II alpha
- protein kinase, cAMP-dependent, regulatory, type 2, alpha
- LOW QUALITY PROTEIN: cAMP-dependent protein kinase type II-alpha regulatory subunit
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