PRKD3 Produkte
(Protein Kinase D3 (PRKD3))
Kategorien
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. [provided by RefSeq, Jul 2008].
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Ausgewählte PRKD3 Kategorien
PRKD3 Antikörper
High quality antibodies with extensive validation data.
PRKD3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PRKD3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN391014
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (5)
Kat. Nr.
ABIN3032380
Menge
0.4 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN391015
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene PRKD3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316291
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN7317099
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5509108
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PRKD3 Produkten
: "Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis." in: Breast cancer research : BCR, Vol. 15, Issue 2, pp. R66, (2014) (PubMed).: "Protein kinase D regulates cofilin activity through p21-activated kinase 4." in: The Journal of biological chemistry, Vol. 286, Issue 39, pp. 34254-61, (2011) (PubMed).
: "Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours." in: Gut, Vol. 59, Issue 10, pp. 1316-30, (2010) (PubMed).
: "PKD3 is the predominant protein kinase D isoform in mouse exocrine pancreas and promotes hormone-induced amylase secretion." in: The Journal of biological chemistry, Vol. 284, Issue 4, pp. 2459-71, (2009) (PubMed).
: "Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells." in: American journal of physiology. Cell physiology, Vol. 296, Issue 4, pp. C821-7, (2009) (PubMed).
: "Lysophosphatidylcholine activates a novel PKD2-mediated signaling pathway that controls monocyte migration." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 29, Issue 9, pp. 1376-82, (2009) (PubMed).
: "Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2." in: Cancer research, Vol. 68, Issue 10, pp. 3844-53, (2008) (PubMed).
: "Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18378-83, (2008) (PubMed).
: "Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species." in: Molecular and cellular biology, Vol. 25, Issue 19, pp. 8520-30, (2005) (PubMed).
: "Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor." in: The Journal of biological chemistry, Vol. 280, Issue 19, pp. 19036-44, (2005) (PubMed).
Synonyme und alternative Namen zu PRKD3
protein kinase D3 (PRKD3), protein kinase D3 (prkd3), protein kinase D3 (Prkd3), 4930557O20Rik, 5730497N19Rik, EPK2, nPKC-NU, PKC-NU, Pkcnu, PKD3, PRKCN, Prkcn, PRKD3Bezeichner auf Proteinebene für PRKD3
- protein kinase C nu type
- protein kinase C, nu
- protein kinase EPK2
- protein-serine/threonine kinase
- serine/threonine-protein kinase D3
- protein kinase D3
- serine/threonine-protein kinase D3-like
- nPKC-nu
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