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PRKDC Produkte

(Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010].

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Ausgewählte PRKDC Kategorien

PRKDC Antikörper

High quality antibodies with extensive validation data.

PRKDC ELISA Kits

Reliable ELISA kits for a wide range of species.

PRKDC Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PRKDC Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC, ICC
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN969366
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IF, IHC (p)
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN519209
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6241643
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PRKDC ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958940
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1381086
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1130280
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PRKDC Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1316293
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7399958
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN5710145
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PRKDC Produkten

Ugidos, Mena, Baquero, Alloza, Azkargorta, Elortza, Vandenbroeck: "Interactome of the Autoimmune Risk Protein ANKRD55." in: Frontiers in immunology, Vol. 10, pp. 2067, (2019) (PubMed).

Biehs, Steinlage, Barton, Juhász, Künzel, Spies, Shibata, Jeggo, Löbrich: "DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination." in: Molecular cell, Vol. 65, Issue 4, pp. 671-684.e5, (2017) (PubMed).

Ha, Ma, Lin, Tang, Lian, Zhao, Li, Zhen, Pei, Han, Malumbres, Jin, Chen, Zhao, Zhu, Zhang: "The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites." in: Nature communications, Vol. 8, pp. 15751, (2017) (PubMed).

Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

Fantini, Huang, Asara, Bagchi, Raychaudhuri: "Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2." in: Molecular biology of the cell, Vol. 28, Issue 1, pp. 192-200, (2016) (PubMed).

Sun, Cheng, Zhu, Zhang, Liu, Xu, Sun, Lv: "Identification of PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide) as an essential gene for colorectal cancer (CRCs) cells." in: Gene, Vol. 584, Issue 1, pp. 90-6, (2016) (PubMed).

Berard, Coombs, Severini: "Quantification of the host response proteome after herpes simplex virus type 1 infection." in: Journal of proteome research, Vol. 14, Issue 5, pp. 2121-42, (2015) (PubMed).

Pyun, Seo, Lee, Jin, Kim, Kim, Kim, Nam, Yook, Lee: "Mutual regulation between DNA-PKcs and Snail1 leads to increased genomic instability and aggressive tumor characteristics." in: Cell death & disease, Vol. 4, pp. e517, (2013) (PubMed).

Schuler, Rübe: "Accumulation of DNA damage-induced chromatin alterations in tissue-specific stem cells: the driving force of aging?" in: PLoS ONE, Vol. 8, Issue 5, pp. e63932, (2013) (PubMed).

Lorat, Schanz, Schuler, Wennemuth, Rübe, Rübe: "Beyond repair foci: DNA double-strand break repair in euchromatic and heterochromatic compartments analyzed by transmission electron microscopy." in: PLoS ONE, Vol. 7, Issue 5, pp. e38165, (2012) (PubMed).

Synonyme und alternative Namen zu PRKDC

protein kinase, DNA-activated, catalytic polypeptide (PRKDC), protein kinase, DNA-activated, catalytic polypeptide L homeolog (prkdc.L), DNA-dependent protein kinase catalytic subunit (LOC100633457), protein kinase, DNA activated, catalytic polypeptide (Prkdc), AI326420, AU019811, DNA-PKcs, DNA-PKCS, dna-pkcs, DNAPDcs, DNAPK, dnapk, DNPK1, dnpk1, DOXNPH, dxnph, HYRC, hyrc, HYRC1, hyrc1, p350, p460, PRKDC, prkdc-A, scid, slip, XRCC7, xrcc7

Bezeichner auf Proteinebene für PRKDC

  • DNA-PK catalytic subunit
  • DNA-dependent protein kinase catalytic subunit
  • hyper-radiosensitivity of murine scid mutation, complementing 1
  • p460
  • protein kinase, DNA-activated, catalytic polypeptide
  • DNA-PKcs
  • protein kinase catalytic subunit (DNA-dependent protein kinase)
  • DNA-activated protein kinase catalytic polypeptide
  • DNA-dependent protein kinase catalytic subunit-like
  • doxorubicin nephropathy
  • severe combined immunodeficiency
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