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PRKG1 Produkte

(Protein Kinase, CGMP-Dependent, Type I (PRKG1))

Kategorien

Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity. [provided by RefSeq, Sep 2011].

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Ausgewählte PRKG1 Kategorien

PRKG1 Antikörper

High quality antibodies with extensive validation data.

PRKG1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PRKG1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PRKG1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN392536
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN562400
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN562402
Menge 100 μg
Datenblatt Datenblatt

Empfohlene PRKG1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969729
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958936
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958937
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PRKG1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316297
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316295
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5509120
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PRKG1 Produkten

Schwappacher, Kilic, Kojonazarov, Lang, Diep, Zhuang, Gawlowski, Schermuly, Pfeifer, Boss, Pilz: "A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16557-66, (2013) (PubMed).

Synonyme und alternative Namen zu PRKG1

protein kinase, cGMP-dependent, type Ia (prkg1a), protein kinase, cGMP-dependent, type I (PRKG1), protein kinase, cGMP-dependent, type I (prkg1), protein kinase, cGMP-dependent, type 1 (Prkg1), protein kinase, cGMP-dependent, type I (Prkg1), 1, AW125416, cGK, cGk1, cGK 1, cGK1, cGKI, CGKI, cGKI-alpha, cGKI-BETA, cGKI-beta, Gm19690, PKG, Pkgi, prkg1, PRKG1B, Prkg1b, Prkg1beta, PRKGR1B, Prkgr1b, zgc:63955

Bezeichner auf Proteinebene für PRKG1

  • cGMP-dependent protein kinase 1
  • protein kinase, cGMP-dependent, type I
  • cGMP-dependent protein kinase 1, beta isozyme
  • cGMP-dependent protein kinase I alpha
  • cGK I alpha
  • cGMP-dependent protein kinase 1-like
  • cGMP dependent protein kinase type 1
  • protein kinase, cGMP-dependent, regulatory, type I, beta
  • CGK 1 alpha
  • cGK 1 beta
  • cGK1
  • cGKI-alpha
  • cGMP-dependent protein kinase 1, alpha isozyme
  • cGMP-dependent protein kinase I
  • cGK 1
  • PKG1 alpha
  • cGMP-dependent protein kinase type 1 alpha
  • cGMP-dependent protein kinase type I beta
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