PRMT6 Produkte
(Protein Arginine Methyltransferase 6 (PRMT6))
Kategorien
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011].
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Ausgewählte PRMT6 Kategorien
PRMT6 Antikörper
High quality antibodies with extensive validation data.
PRMT6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PRMT6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (5)
Kat. Nr.
ABIN949428
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (5)
Kat. Nr.
ABIN3032363
Menge
0.4 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7165075
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PRMT6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951336
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PRMT6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124643
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316337
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316339
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PRMT6 Produkten
: "The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1-IRF3 signaling." in: Cellular & molecular immunology, (2018) (PubMed).: "PRMT4 is involved in insulin secretion via the methylation of histone H3 in pancreatic β cells." in: Journal of molecular endocrinology, Vol. 54, Issue 3, pp. 315-24, (2015) (PubMed).
: "PELP1 oncogenic functions involve alternative splicing via PRMT6." in: Molecular oncology, Vol. 8, Issue 2, pp. 389-400, (2014) (PubMed).
: "A gain-of-function mouse model identifies PRMT6 as a NF-κB coactivator." in: Nucleic acids research, Vol. 42, Issue 13, pp. 8297-309, (2014) (PubMed).
: "Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor." in: Nucleic acids research, Vol. 40, Issue 19, pp. 9513-21, (2012) (PubMed).
: "Activity-based protein profiling of protein arginine methyltransferase 1." in: ACS chemical biology, Vol. 6, Issue 10, pp. 1127-35, (2011) (PubMed).
: "Regulation of post-translational protein arginine methylation during HeLa cell cycle." in: Biochimica et biophysica acta, Vol. 1800, Issue 9, pp. 977-85, (2010) (PubMed).
: "Proteomic identification and comparative analysis of asymmetrically arginine-methylated proteins in immortalized, young and senescent cells." in: Electrophoresis, Vol. 31, Issue 23-24, pp. 3823-33, (2010) (PubMed).
: "Arginine methylation regulates telomere length and stability." in: Molecular and cellular biology, Vol. 29, Issue 18, pp. 4918-34, (2009) (PubMed).
: "Human protein arginine methyltransferases in vivo--distinct properties of eight canonical members of the PRMT family." in: Journal of cell science, Vol. 122, Issue Pt 5, pp. 667-77, (2009) (PubMed).
Synonyme und alternative Namen zu PRMT6
Arginine methyltransferase 6 (Art6), protein arginine methyltransferase 6 (PRMT6), protein arginine methyltransferase 6 S homeolog (prmt6.S), arginine N-methyltransferase, type I (PRMT6), protein arginine methyltransferase 6 (prmt6), protein arginine methyltransferase 6 (Prmt6), protein arginine N-methyltransferase 6 (Prmt6), ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6, ATPRMT6, AW124876, BB233495, CG9927, DART6, DKFZp459B1431, Dmel\\CG9927, HRMT1L6, Hrmt1l6, hrmt1l6, hrmt6, im:6908706, PRMT6, protein arginine methyltransferase 6Bezeichner auf Proteinebene für PRMT6
- arginine methyltransferase 6
- CG9927-PA
- Art6-PA
- protein arginine methyltransferase 6
- HMT1 hnRNP methyltransferase-like 6
- Histone-arginine N-methyltransferase PRMT6
- protein arginine N-methyltransferase 6
- arginine N-methyltransferase, type I
- heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6
- histone-arginine N-methyltransferase PRMT6
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