PRNP Produkte
(Prion Protein (PRNP))
Kategorien
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].
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Ausgewählte PRNP Kategorien
PRNP Antikörper
High quality antibodies with extensive validation data.
PRNP ELISA Kits
Reliable ELISA kits for a wide range of species.
PRNP Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PRNP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7433921
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, FACS
Validierungen
- (4)
Kat. Nr.
ABIN7193415
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7260569
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene PRNP ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969500
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969499
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958725
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PRNP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275480
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7275481
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316351
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PRNP Produkten
: "Altered levels of plasma neuron-derived exosomes and their cargo proteins characterize acute and chronic mild traumatic brain injury." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 4, pp. 5082-5088, (2020) (PubMed).: "Effects of cellular prion protein on rapid eye movement sleep deprivation-induced spatial memory impairment." in: Journal of integrative neuroscience, Vol. 18, Issue 4, pp. 439-444, (2020) (PubMed).
: "Atypical scrapie in Australia." in: Australian veterinary journal, Vol. 94, Issue 12, pp. 452-455, (2016) (PubMed).
: "Geno- and phenotyping of human neutrophil antigens." in: Methods in molecular biology (Clifton, N.J.), Vol. 1310, pp. 193-203, (2016) (PubMed).
: "Allelic variants at codon 146 in the PRNP gene show significant differences in the risk for natural scrapie in Cypriot goats." in: Epidemiology and infection, Vol. 143, Issue 6, pp. 1304-10, (2015) (PubMed).
: "Polo-like kinase 3 (PLK3) mediates the clearance of the accumulated PrP mutants transiently expressed in cultured cells and pathogenic PrP(Sc) in prion infected cell line via protein interaction." in: The international journal of biochemistry & cell biology, Vol. 62, pp. 24-35, (2015) (PubMed).
: "Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay." in: The Journal of biological chemistry, Vol. 290, Issue 27, pp. 17020-8, (2015) (PubMed).
: "The prion protein inhibits monocytic cell migration by stimulating β1 integrin adhesion and uropod formation." in: Journal of cell science, Vol. 128, Issue 16, pp. 3018-29, (2015) (PubMed).
: "Detection of the GPI-anchorless prion protein fragment PrP226* in human brain." in: BMC neurology, Vol. 13, pp. 126, (2013) (PubMed).
: "The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6." in: The Journal of biological chemistry, Vol. 288, Issue 52, pp. 37241-55, (2013) (PubMed).
Synonyme und alternative Namen zu PRNP
prion protein (PRNP), prion protein (Prnp), prion protein S homeolog (prnp.S), prion protein b (prnpb), AA960666, AI325101, AltPrP, ASCR, CD230, CJD, cjd, GSS, KURU, MGC84114, p27-30, prion, PRIP, Prn, Prn-i, Prn-p, PRNP, prnprs1, PrP, prp, PRP, Prp, prp(c), PrP-1, PrP1, PrP27-30, prP27-30, PrP33-35C, prP33-35C, PrPBezeichner auf Proteinebene für PRNP
- CD230 antigen
- major prion protein
- prion-related protein
- prion protein, PrP
- prion protein, structural
- major scrapie-associated fibril protein 1
- prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)
- prion protein PrP
- prion protein precursor PrP
- prion protein variant a
- prion protein variant b
- 65-21 protein
- ARIA
- PR-LP
- acetylcholine receptor-inducing activity
- major prion protein homolog
- prion-like protein
- prion-like-protein
- prion protein
- infectious amyloid
- Major prion protein
- major prion protein preproprotein
- prP
- prP27-30
- prP33-35C
- PrP 27-30
- prion protein 1
- prion protein b
- prion protein, related sequence 1
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