Prosaposin Produkte
(Prosaposin (PSAP))
Kategorien
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte Prosaposin Kategorien
Prosaposin Antikörper
High quality antibodies with extensive validation data.
Prosaposin ELISA Kits
Reliable ELISA kits for a wide range of species.
Prosaposin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Prosaposin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, FACS, ICC
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN1098150
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC, IP
Validierungen
- (10)
Kat. Nr.
ABIN7435130
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, IHC, ELISA, FACS, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7193617
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Prosaposin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958859
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951184
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730233
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Prosaposin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN1316504
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124603
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316506
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Prosaposin Produkten
: "Putative Biomarkers for Malignant Pleural Mesothelioma Suggested by Proteomic Analysis of Cell Secretome." in: Cancer genomics & proteomics, Vol. 17, Issue 3, pp. 225-236, (2020) (PubMed).: "Prosaposin in seminal plasma on the day of oocyte retrieval is associated with normal fertilization and embryo development in in vitro fertilization cycles." in: PeerJ, Vol. 7, pp. e8177, (2019) (PubMed).
: "Prosaposin is a regulator of progranulin levels and oligomerization. ..." in: Nature communications, Vol. 7, pp. 11992, (2016) (PubMed).
: "Prosaposin activates the androgen receptor and potentiates resistance to endocrine treatment in breast cancer." in: Breast cancer research : BCR, Vol. 17, Issue 1, pp. 123, (2015) (PubMed).
: "Decrease in prosaposin in spermatozoon is associated with polychlorinated biphenyl exposure." in: International journal of clinical and experimental pathology, Vol. 8, Issue 3, pp. 2436-48, (2015) (PubMed).
: "Mesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formation." in: The Journal of biological chemistry, Vol. 289, Issue 29, pp. 20026-38, (2014) (PubMed).
: "Serum prosaposin levels are increased in patients with advanced prostate cancer." in: The Prostate, Vol. 72, Issue 3, pp. 253-69, (2012) (PubMed).
: "Prosaposin, a regulator of estrogen receptor alpha, promotes breast cancer growth." in: Cancer science, Vol. 103, Issue 10, pp. 1820-5, (2012) (PubMed).
: "The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells." in: The Biochemical journal, Vol. 441, Issue 2, pp. 665-74, (2011) (PubMed).
: "Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion." in: Molecular cancer, Vol. 9, pp. 30, (2010) (PubMed).
Synonyme und alternative Namen zu Prosaposin
prosaposin (PSAP), prosaposin (Psap), prosaposin (psap), prosaposin (LOC100011417), prosaposin (LOC100304726), prosaposin (LOC100526719), surfactant protein A1 (SFTPA1), AI037048, cb759, GLBA, PSAP, PSP-A, SAP1, SFTPA1B, SGP-1, SGP1A, SP-A, wu:fa14a06, wu:fb36e02, wu:fb58g07Bezeichner auf Proteinebene für Prosaposin
- proactivator polypeptide
- sphingolipid activator protein-1
- snoRNA MBII-198
- sulfated glycoprotein 1
- prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator)
- prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)
- prosaposin
- proactivator polypeptide-like
- pulmonary surfactant-associated protein A
- surfactant protein A
- surfactant protein A1B
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