CD8B Protein (AA 22-170) (His tag)

Produktnummer ABIN1096341

Produktdetails

Target: CD8B (CD8b Molecule (CD8B))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-170

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CD8B Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CD8 β Chain/CD8B (C-6His)

Sequenz: LQQTPAYIKV QTNKMVMLSC EAKISLSNMR IYWLRQRQAP SSDSHHEFLA LWDSAKGTIH GEEVEQEKIA VFRDASRFIL NLTSVKPEDS GIYFCMIVGS PELTFGKGTQ LSVVDFLPTT AQPTKKSTLK KRVCRLPRPE TQKGPLCSPV DHHHHHH

Produktmerkmale:

Recombinant Human CD8 β Chain/CD8B (C-6His)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD8B (CD8b Molecule (CD8B))

Andere Bezeichnung: T-Cell Surface Glycoprotein CD8beta Chain/CD8B (CD8B Produkte)

Synonyme: Cd8b Protein, Ly-3 Protein, Ly-C Protein, Lyt-3 Protein, CD8B1 Protein, LEU2 Protein, LY3 Protein, LYT3 Protein, P37 Protein, Cd8b1 Protein, CD8b molecule Protein, CD8 antigen, beta chain 1 Protein, Cd8b Protein, CD8B Protein, Cd8b1 Protein

Hintergrund: Recombinant Human T-Cell Surface Glycoprotein CD8β Chain/CD8B is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Leu22-Pro170) of Human CD8B fused with a polyhistidine tag at the C-terminus.
T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two α chains, or a heterodimer composed of one α and one β chain. Both α and β chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Molekulargewicht: 17.8 kDa

UniProt: P10966

Pathways: T-Zell Rezeptor Signalweg