Desmin Protein (DES) (AA 260-470) (His tag)

Produktnummer ABIN1096527

Produktdetails

Target: Desmin (DES)

Protein-Typ: Recombinant

Proteineigenschaft: AA 260-470

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Desmin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Desmin (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MVEMDMSKPD LTAALRDIRA QYETIAAKNI SEAEEWYKSK VSDLTQAANK NNDALRQAKQ EMMEYRHQIQ SYTCEIDALK GTNDSLMRQM RELEDRFASE ASGYQDNIAR LEEEIRHLKD EMARHLREYQ DLLNVKMALD VEIATYRKLL EGEESRINLP IQTYSALNFR ETSPEQRGSE VHTKKTVMIK TIETRDGEVV SEATQQQHEV L

Produktmerkmale: Recombinant Human Desmin is produced by our E. coli expression system. The target protein is expressed with sequence (Val260-Leu470) of Human DES fused with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: Desmin (DES)

Andere Bezeichnung: Desmin (DES Produkte)

Synonyme: DES Protein, des-b Protein, MGC80853 Protein, des Protein, csm1 Protein, csm2 Protein, desm Protein, cmd1i Protein, MGC75911 Protein, LOC100220724 Protein, desmin Protein, cb290 Protein, fb59a12 Protein, wu:fb59a12 Protein, zgc:109859 Protein, CSM1 Protein, CSM2 Protein, LGMD2R Protein, wu:fc11d08 Protein, zgc:154009 Protein, des-a Protein, MGC52614 Protein, desmin Protein, desmin, gene 1 L homeolog Protein, desmin, gene 1 Protein, desmin a Protein, desmin b Protein, desmin, gene 1 S homeolog Protein, desmin, gene 2 S homeolog Protein, DES Protein, des.1.L Protein, des.1 Protein, des Protein, desma Protein, Des Protein, desmb Protein, des.1.S Protein, des.2.S Protein

Sub Type: Fusionprotein

Hintergrund: Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.
Alternative Names: Desmin, DES

Molekulargewicht: 26.7 kDa

UniProt: P17661