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MOG Protein (AA 30-154)

MOG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Func Active
Produktnummer ABIN1097170
  • Target Alle MOG Proteine anzeigen
    MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 30-154
    Spezies
    • 9
    • 4
    • 2
    • 1
    Human
    Quelle
    • 7
    • 5
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    Functional Studies (Func)
    Verwendungszweck
    Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG
    Sequenz
    MGQFRVIGPR HPIRALVGDE VELPCRISPG KNATGMEVGW YRPPFSRVVH LYRNGKDQDG DQAPEYRGRT ELLKDAIGEG KVTLRIRNVR FSDEGGFTCF FRDHSYQEEA AMELKVEDPF YWVSPGHHHH HH
    Produktmerkmale
    Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG is produced with our E. coli expression system. The target protein is expressed with sequence (Gly30-Gly154) of Human MOG protein.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product MOG Protein
  • Kommentare

    Biological activity: Tested for capability to induce EAE in rodents and monkeys

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.5.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    3 months
  • Target
    MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
    Andere Bezeichnung
    mog-protein (MOG Produkte)
    Synonyme
    MOGIG2 Protein, NRCLP7 Protein, B230317G11Rik Protein, MOG Protein, myelin oligodendrocyte glycoprotein Protein, MOG Protein, Mog Protein
    Hintergrund
    Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.
    Alternative Names: Myelin-Oligodendrocyte Glycoprotein, MOG
    Molekulargewicht
    15.2 kDa
    UniProt
    Q16653
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