MVK Protein (His tag)

Produktnummer ABIN1098525

Produktdetails

Target: MVK (Mevalonate Kinase (MVK))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MVK Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Mevalonate kinase, LRBP, MK, MVLK

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: MVK (Mevalonate Kinase (MVK))

Andere Bezeichnung: MVK (MVK Produkte)

Synonyme: F21A20.160 Protein, F21A20_160 Protein, MEVALONATE KINASE Protein, MVK Protein, mevalonate kinase Protein, DDBDRAFT_0168621 Protein, DDBDRAFT_0302479 Protein, DDB_0168621 Protein, DDB_0302479 Protein, LRBP Protein, MK Protein, MVLK Protein, POROK3 Protein, 2310010A05Rik Protein, AI256848 Protein, AI414037 Protein, zgc:103473 Protein, mevalonate kinase Protein, mvk Protein, hypothetical protein Protein, MVK Protein, MK Protein, MA_RS03165 Protein, PAB_RS02890 Protein, LMOf2365_0011 Protein, mvk Protein, RCI_RS14145 Protein, TGAM_RS08735 Protein, MMAH_RS07705 Protein, TAGG_RS01605 Protein, SHELL_RS02965 Protein, MVOL_RS03085 Protein, Igag_1464 Protein, VDIS_RS11260 Protein, MFER_RS04560 Protein, DESMU_RS01555 Protein, ARCVE_RS02955 Protein, MZHIL_RS05110 Protein, Mvk Protein

Hintergrund: Mevalonate kinase, also known as MVK, belongs to the GHMP kinase family. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive,hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Recombinant human MVK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 44.8 kDa (419aa) confirmed by MALDI-TOF

NCBI Accession: NP_001107657