Ephrin B3 Protein (EFNB3) (AA 28-226) (His tag)

Produktnummer ABIN1098662

Dieses Recombinant Ephrin B3-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Ephrin B3 Protein (EFNB3) (AA 28-226) (His tag) (ABIN1098662)

Target: Ephrin B3 (EFNB3)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 28-226

Aufreinigungstag / Konjugat: Dieses Ephrin B3 Protein ist gelabelt mit His tag.

Sequenz: LSLEP VYWNSANKRF QAEGGYVLYP QIGDRLDLLC PRARPPGPHS SPNYEFYKLY LVGGAQGRRC EAPPAPNLLL TCDRPDLDLR FTIKFQEYSP NLWGHEFRSH HDYYIIATSD GTREGLESLQ GGVCLTRGMK VLLRVGQSPR GGAVPRKPVS EMPMERDRGA AHSLEPGKEN LPGDPTSNAT SRGAEGPLPP PSMP

Aufreinigung: > 90% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Synonyms: Ephrin-B3, EFL6, EPLG8, LERK8

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol, 0.1M NaCl, 2M urea

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Ephrin B3 (EFNB3)

Andere Bezeichnung: Ephrin-B3

Hintergrund: EFNB3, also known as ephrin-B3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. Recombinant human EFNB3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Molekulargewicht: 24.6 kDa (224aa)

NCBI Accession: NP_001397

Pathways: RTK Signalweg