HFE Protein (His tag)
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- Target Alle HFE Proteine anzeigen
- HFE (Hemochromatosis (HFE))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses HFE Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 85 % by SDS - PAGE
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Hemochromatosis (HFE) (AA 115-205) protein (GST tag)
HFE Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Hemochromatosis (HFE) proteinHFE Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % pure SDS
Hemochromatosis (HFE) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HFE Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Hemochromatosis (HFE) (Transcript Variant 6) protein (Myc-DYKDDDDK Tag)HFE Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Hemochromatosis (HFE) (Transcript Variant 9) protein (Myc-DYKDDDDK Tag)HFE Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Kommentare
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Synonyms: Hereditary hemochromatosis protein, HFE1, HH, HLA-H, MVCD7, TFQTL2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- HFE (Hemochromatosis (HFE))
- Andere Bezeichnung
- HFE (HFE Produkte)
- Synonyme
- HFE1 Protein, HH Protein, HLA-H Protein, MVCD7 Protein, TFQTL2 Protein, MR2 Protein, hemochromatosis Protein, HFE Protein, Hfe Protein
- Hintergrund
- HFE, also known as HLA-H, belongs to the MHC class I family. This protein contains 1 Ig-like C1-type (immunoglobulin-like) domain. HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor (TFR) with transferrin. It binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. Recombinant human HFE protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 35.7kDa (308aa)
- NCBI Accession
- NP_000401
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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