CXCL10 Protein
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- Target Alle CXCL10 Proteine anzeigen
- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Applikation
- ELISA
- Marke
- BD Pharmingen™
- Spezifität
- Biological Activity: This preparation of recombinant human IP-10 protein has not been evaluated for biological activity. Carrier proteins should be pre-screened for possible effects in an appropriate experimental system. Carrier proteins may effect experimental results due to toxicity, high endotoxin levels or possible blocking activity.
- Produktmerkmale
- The recombinant human IP-10 was produced and found to be ≥ 95% pure by SDS-PAGE analysis and visualized by silver strain.
- Aufreinigung
- The recombinant human IP-10 was produced and found to be ≥ 95 % pure by SDS-PAGE analysis and visualized by silver strain.
- Reinheit
- ≥ 95 %
- Sterilität
- 0.22 μm filtered
- Top Product
- Discover our top product CXCL10 Protein
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- Applikationshinweise
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ELISA Standard: The recombinant human IP-10 (Cat. No. 551130) is useful as a quantitative standard for a sandwich ELISA for measuring human IP-10 protein levels. Purified 4D5 antibody (Cat. No. 555046) can be paired with the biotinylated 6D4 antibody (Cat. No. 555048) with recombinant human IP-10 as the standard. To obtain linear standard curves, doubling dilutions of human IP-10 ranging from ~1,000 to 5 pg/ml are recommended for inclusion in each ELISA plate.
Note: This ELISA pair is recommended primarily for measuring cytokine from experimental cell culture systems. These ELISA reagents are not recommended for assaying serum or plasma samples. For measuring human-IP-10 in serum or plasma our BD OptEIA™ Human IP-10 Set (Cat. No. 550926) is specially formulated and recommended. - Kommentare
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BD Pharmingen™ Recombinant Human IP-10
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konservierungsmittel
- Azide free
- Handhabung
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This preparation contains no preservatives, thus it should be handled under aseptic conditions. Recombinant human IP-10 is supplied lyophilized from a solution of aqueous buffered solution containing 50 µg BSA per 1 µg of cytokine as carrier protein. No sodium azide has been added to the preparation and the endotoxin level is less than 1 EU per 1 µg of the cytokine as determined by the LAL method. The product can be reconstituted in sterile neutral buffer containing not less than 0.5 - 10.0 mg/ml carrier protein such as human or bovine serum albumin, aliquoted into polypropylene microtubes and stored at -80°C.
Note: Failure to add carrier protein or store at indicated temperatures may result in a loss of activity. - Lagerung
- -80 °C
- Informationen zur Lagerung
- This preparation contains no preservatives, thus it should be handled under aseptic conditions. Store product at -80°C prior to use or for long term storage of stock solutions. Avoid multiple freeze-thaws of product. Recombinant human IP-10 is supplied lyophilized from a solution of aqueous buffered solution containing 50 μg BSA per 1 μg of cytokine as carrier protein. No sodium azide has been added to the preparation and the endotoxin level is less than 1 EU per 1 μg of the cytokine as determined by the LAL method. The product can be reconstituted in sterile neutral buffer containing not less than 0.5 - 10.0 mg/ml carrier protein such as human or bovine serum albumin, aliquoted into polypropylene microtubes and stored at -80°C. NOTE: Failure to add carrier protein** or store at indicated temperatures may result in a loss of activity.
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Mig and IP-10: CXC chemokines that target lymphocytes." in: Journal of leukocyte biology, Vol. 61, Issue 3, pp. 246-57, (1997) (PubMed).
: "Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes." in: The Journal of experimental medicine, Vol. 184, Issue 3, pp. 963-9, (1997) (PubMed).
: "Biochemical characterization of a gamma interferon-inducible cytokine (IP-10)." in: The Journal of experimental medicine, Vol. 166, Issue 4, pp. 1084-97, (1987) (PubMed).
: "Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 9, pp. 2868-71, (1987) (PubMed).
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Mig and IP-10: CXC chemokines that target lymphocytes." in: Journal of leukocyte biology, Vol. 61, Issue 3, pp. 246-57, (1997) (PubMed).
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- Target
- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
- Andere Bezeichnung
- IP-10 (CXCL10 Produkte)
- Synonyme
- CXCL10 Protein, C7 Protein, IFI10 Protein, INP10 Protein, IP-10 Protein, SCYB10 Protein, crg-2 Protein, gIP-10 Protein, mob-1 Protein, CRG-2 Protein, IP10 Protein, Ifi10 Protein, Scyb10 Protein, C-X-C motif chemokine ligand 10 Protein, C-X-C motif chemokine 10 Protein, chemokine (C-X-C motif) ligand 10 Protein, CXCL10 Protein, cxl10 Protein, Cxcl10 Protein
- Hintergrund
- Interferon-γ inducible protein-10 (IP-10) is a 10 kD protein that belongs to CXC chemokine family. Unlike other CXC chemokines, IP-10 is a chemoattractant for activated lymphocytes, but not resting lymphocytes or neutrophils. The gene for human IP-10 has been mapped to chromosome 4q2. CXC chemokine receptor 3 (CXCR3) has been identified as the receptor for IP-10.
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