FGF21 Protein (AA 1-209) (Fc Tag)
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- Target Alle FGF21 Proteine anzeigen
- FGF21 (Fibroblast Growth Factor 21 (FGF21))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 1-209
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses FGF21 Protein ist gelabelt mit Fc Tag.
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Human
- Produktmerkmale
- Human FGF-21 (aa 1-209) is fused at the C-terminus to the Fc portion of human IgG1.
- Reinheit
- >95 % (SDS-PAGE)
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FGF21 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Haltbarkeit
- 3 months
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- Target
- FGF21 (Fibroblast Growth Factor 21 (FGF21))
- Andere Bezeichnung
- FGF-21 (FGF21 Produkte)
- Synonyme
- FGF21 Protein, fibroblast growth factor 21 Protein, FGF21 Protein, fgf21 Protein, Fgf21 Protein
- Hintergrund
- FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho.
- Molekulargewicht
- ~50kDa (SDS-PAGE)
- UniProt
- Q9NSA1
- Pathways
- RTK Signalweg
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