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Calreticulin Protein (CALR) (His tag)

CALR Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >90 % (SDS-PAGE) SDS
Produktnummer ABIN1344123
  • Target Alle Calreticulin (CALR) Proteine anzeigen
    Calreticulin (CALR)
    Protein-Typ
    Recombinant
    Spezies
    • 10
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 14
    • 11
    • 3
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses Calreticulin Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Human calreticulin (aa18-417) is fused at the C-terminus to a His-tag.
    Reinheit
    >90 % (SDS-PAGE)
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    <1EU/μg purified protein (LAL test, Lonza).
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Working aliquots are stable for up to 3 months when stored at -20°C.
    Haltbarkeit
    3 months
  • Target
    Calreticulin (CALR)
    Andere Bezeichnung
    Calreticulin (CALR Produkte)
    Synonyme
    CRT Protein, RO Protein, SSA Protein, cC1qR Protein, crc Protein, crt Protein, Calregulin Protein, CG9429 Protein, Clr Protein, Dmel\\CG9429 Protein, anon-EST:Liang-2.11 Protein, anon-EST:Liang-2.17 Protein, anon-EST:fe3D7 Protein, clone 2.11 Protein, clone 2.17 Protein, eth Protein, potp Protein, cc1qr Protein, ssa Protein, NV19007 Protein, CRP55 Protein, ERp60 Protein, HACBP Protein, CHOT1 Protein, CHT1 Protein, CT1 Protein, AA589632 Protein, CRTR Protein, Creat Protein, CCDS1 Protein, calrl2 Protein, fc66d10 Protein, wu:fc66d10 Protein, wu:fj50c03 Protein, zgc:66153 Protein, calreticulin Protein, calreticulin L homeolog Protein, Calreticulin Protein, putative calreticulin Protein, solute carrier family 6 member 8 Protein, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Protein, CALR Protein, calr.L Protein, Crt Protein, crt Protein, CRT Protein, Calr Protein, calr Protein, LMJF_31_2600 Protein, Crc Protein, Slc6a8 Protein, SLC6A8 Protein, LOC8269812 Protein
    Hintergrund
    Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
    Molekulargewicht
    ~55kDa (SDS-PAGE)
    UniProt
    P27797
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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