TNFRSF11A Protein (AA 31-214) (Fc Tag)
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- Target Alle TNFRSF11A Proteine anzeigen
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 31-214
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Spezies
- Human, Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses TNFRSF11A Protein ist gelabelt mit Fc Tag.
- Applikation
- SDS-PAGE (SDS)
- Spezifität
- Binds to mouse and human RANKL.
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Mouse RANK (aa 31-214) is fused at the C-terminus to the Fc portion of human IgG1.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFRSF11A Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Inhibits mouse and human RANKL biological functions.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 50 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
- Andere Bezeichnung
- RANK (TNFRSF11A Produkte)
- Synonyme
- RANK Protein, RGD1563614 Protein, TNFRSF11A Protein, Ly109 Protein, ODFR Protein, OFE Protein, Rank Protein, TRANCE-R Protein, mRANK Protein, CD265 Protein, FEO Protein, LOH18CR1 Protein, OPTB7 Protein, OSTS Protein, PDB2 Protein, TRANCER Protein, TNF receptor superfamily member 11A Protein, TNF receptor superfamily member 11a Protein, tumor necrosis factor receptor superfamily, member 11a, NFKB activator Protein, Tnfrsf11a Protein, TNFRSF11A Protein
- Hintergrund
- RANK (TRANCE-R, CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.
- Molekulargewicht
- ~55kDa (SDS-PAGE)
- UniProt
- O35305
- Pathways
- NF-kappaB Signalweg
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