APEX1 Protein (AA 1-318) (GST tag)
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- Target Alle APEX1 Proteine anzeigen
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-318
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Spezies
- Human
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Quelle
- Wheat germ
- Aufreinigungstag / Konjugat
- Dieses APEX1 Protein ist gelabelt mit GST tag.
- Applikation
- Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)
- Verwendungszweck
- APEX1 (Human) Recombinant Protein (P01)
- Sequenz
- MPKRGKKGAV AEDGDELRTE PEAKKSKTAA KKNDKEAAGE GPALYEDPPD QKTSPSGKPA TLKICSWNVD GLRAWIKKKG LDWVKEEAPD ILCLQETKCS ENKLPAELQE LPGLSHQYWS APSDKEGYSG VGLLSRQCPL KVSYGIGEEE HDQEGRVIVA EFDSFVLVTA YVPNAGRGLV RLEYRQRWDE AFRKFLKGLA SRKPLVLCGD LNVAHEEIDL RNPKGNKKNA GFTPQERQGF GELLQAVPLA DSFRHLYPNT PYAYTFWTYM MNARSKNVGW RLDYFLLSHS LLPALCDSKI RSKALGSDHC PITLYLAL
- Produktmerkmale
- Human APEX1 full-length ORF ( AAH02338, 1 a.a. - 318 a.a.) recombinant protein with GST-tag at N-terminal.
- Aufreinigung
- in vitro wheat germ expression system
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- Handhabung
- Aliquot to avoid repeated freezing and thawing.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Best use within three months from the date of receipt of this protein.
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Bcl2 inhibits abasic site repair by down-regulating APE1 endonuclease activity." in: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9925-32, (2008) (PubMed).
: "
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Bcl2 inhibits abasic site repair by down-regulating APE1 endonuclease activity." in: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9925-32, (2008) (PubMed).
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- Target
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- Andere Bezeichnung
- APEX1 (APEX1 Produkte)
- Synonyme
- apex1 Protein, MGC76280 Protein, MGC79645 Protein, MGC78928 Protein, APE Protein, APE1 Protein, APEN Protein, APEX Protein, APX Protein, HAP1 Protein, REF1 Protein, Apex Protein, REF-1 Protein, BAP1 Protein, apex1a Protein, hm:zehn1532 Protein, wu:fc13d11 Protein, zgc:66204 Protein, Ref-1 Protein, apurinic/apyrimidinic endodeoxyribonuclease 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog Protein, DNA-(apurinic or apyrimidinic site) lyase Protein, apurinic/apyrimidinic endonuclease 1 Protein, APEX1 Protein, apex1 Protein, apex1.L Protein, CNG03640 Protein, CNH01280 Protein, nth Protein, Spirs_4119 Protein, Palpr_0103 Protein, Apex1 Protein
- Hintergrund
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Full Gene Name: APEX nuclease (multifunctional DNA repair enzyme) 1
Synonyms: APE,APE-1,APE1,APEN,APEX,APX,HAP1,REF-1,REF1 - Gen-ID
- 328
- Pathways
- DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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