HSPE1 Protein

Produktnummer ABIN1686730

Produktdetails

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Western Blotting (WB), SDS-PAGE (SDS)

Sequenz: MAGQAFRKFL PLFDRVLVER SAAETVTKGG IMLPEKSQGK VLQATVVAVG SGSKGKGGEI QPVSVKVGDK VLLPEYGGTK VVLDDKDYFL FRDGDILGKY VD

Spezifität: ~10 kDa

Aufreinigung: Multi-Step Purified

Reinheit: >90%

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

This product has been certified >90% pure using SDS-PAGE analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: 20 mM Tris, pH 7.5, 0.3M NaCl, 10 % glycerol, 1 mM DTT

Lagerung: -20 °C

Referenzen

Kaiser, Steptoe, Thompson, Henderson: "Monocyte cytokine synthesis in response to extracellular cell stress proteins suggests these proteins exhibit network behaviour." in: Cell stress & chaperones, Vol. 19, Issue 1, pp. 135-44, (2013) (PubMed).

Antigendetails

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Andere Bezeichnung: Cpn10 (HSPE1 Produkte)

Synonyme: CPN10 Protein, EPF Protein, GROES Protein, HSP10 Protein, groS Protein, Cpn10 Protein, cpn10 Protein, zgc:86747 Protein, hspe1 Protein, MGC89647 Protein, HSPE1 Protein, MITOCHONDRIAL CHAPERONIN 10 Protein, T15D22.2 Protein, T15D22_2 Protein, chaperonin 10 Protein, Dmel\\CG11267 Protein, Hsp10 Protein, anon-WO0118547.175 Protein, hsp10 Protein, crpB Protein, chpS Protein, 10kDa Protein, mt-cpn10 Protein, heat shock protein family E (Hsp10) member 1 Protein, molecular chaperone GroES Protein, chaperonin 10 kDa Protein, chaperonin, 10 kDa Protein, chaperonin-10 kDa Protein, heat shock protein family E member 1 Protein, heat shock 10 protein 1 Protein, heat shock protein family E (Hsp10) member 1 L homeolog Protein, heat shock 10kDa protein 1 (chaperonin 10) pseudogene Protein, 10 kd chaperonin Protein, chaperonin 10 Protein, Hsp10p Protein, co-chaperonin 10, mitochondrial Protein, CG11267 gene product from transcript CG11267-RA Protein, co-chaperonin GroES Protein, mitochondrial heat shock protein Hsp10 (predicted) Protein, chaperonin GroS Protein, Hsp10 10 kDa chaperonin GROES Protein, mitochondrial heat shock protein Hsp10 Protein, heat shock protein 10 Protein, heat shock protein 1 (chaperonin 10) Protein, heat shock 10kDa protein 1 (chaperonin 10) Protein, HSPE1 Protein, groES Protein, groES2 Protein, TP01_0190 Protein, Cag_1167 Protein, Bm1_56470 Protein, Hspe1 Protein, hspe1 Protein, hspe1.L Protein, LOC452179 Protein, Cpn10 Protein, CPN10 Protein, HSP10 Protein, CG11267 Protein, hsp10 Protein, groS Protein

Hintergrund: Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10 kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process (1). Cpn10 has been located in human platelets, but is also present in human maternal serum (2, 3). It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy (4).

Molekulargewicht: approx. 10 kDa

Gen-ID: 3336

NCBI Accession: NM_002157

UniProt: P61604

Pathways: Positive Regulation of Endopeptidase Activity