RHEB Protein (AA 1-184) (GST tag)
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- Target Alle RHEB Proteine anzeigen
- RHEB (Ras Homolog Enriched in Brain (RHEB))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-184
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses RHEB Protein ist gelabelt mit GST tag.
- Verwendungszweck
- Recombinant Human GTP-Binding Protein Rheb/RHEB (N-GST)
- Sequenz
- MPQSKSRKIA ILGYRSVGKS SLTIQFVEGQ FVDSYDPTIE NTFTKLITVN GQEYHLQLVD TAGQDEYSIF PQTYSIDING YILVYSVTSI KSFEVIKVIH GKLLDMVGKV QIPIMLVGNK KDLHMERVIS YEEGKALAES WNAAFLESSA KENQTAVDVF RRIILEAEKM DGAASQGKSS CSVM
- Produktmerkmale
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Recombinant Human GTP-Binding Protein Rheb/RHEB (N-GST)
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product RHEB Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 10 mM GSH, pH 8.0.
- Handhabung
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Lagerung
- 4 °C/-20 °C/-80 °C
- Informationen zur Lagerung
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- RHEB (Ras Homolog Enriched in Brain (RHEB))
- Andere Bezeichnung
- GTP-Binding Protein Rheb/RHEB (RHEB Produkte)
- Synonyme
- RHEB2 Protein, RHEB Protein, rheb2 Protein, CG1081 Protein, DReb Protein, Dm Rheb Protein, DmRheb Protein, Dmel\CG1081 Protein, Q9VND8 Protein, RheB Protein, dRheb Protein, rheb Protein, Ras homolog, mTORC1 binding Protein, Ras homolog enriched in brain Protein, ras homolog enriched in brain Protein, Ras homolog, mTORC1 binding L homeolog Protein, RHEB Protein, Rheb Protein, rheb Protein, rheb.L Protein
- Hintergrund
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Recombinant Human GTP-Binding Protein Rheb/RHEB is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Met184) of Human RHEB fused with a GST tag at the N-terminus.
GTP-Binding Protein Rheb (RHEB) is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. Highest levels of RHEB can be found in the skeletal and cardiac muscle, and it is vital in the regulation of growth and cell cycle progression due to its role in the Insulin/TOR/S6K signaling pathway. RHEB stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling, and it activates the protein kinase activity of mTORC1. RHEB has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, farnesylation of the protein is required for this activity. - Molekulargewicht
- 20.4 kDa
- UniProt
- Q15382
- Pathways
- RTK Signalweg
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