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PARP1 Protein

PARP1 Spezies: Human Wirt: Baculovirus Recombinant > 95 % WB, ELISA, PAR Active
Produktnummer ABIN1741729
  • Target Alle PARP1 Proteine anzeigen
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 11
    • 3
    Human
    Quelle
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Baculovirus
    Applikation
    Western Blotting (WB), ELISA, Poly ADP ribose research (PAR)
    Spezifität
    Biological Activity: 20000 U/mg PARP1,Protein targets
    Produktmerkmale
    PARP1 Enzyme is highly purified and enzymatically active human PARP1, expressed in a baculovirus expression system. It is useful for high-throughput enzymatic assays, visualization of the automodification reaction by SDS-PAGE and Western blotting, ELISA, standard for SDS-PAGE and WB, and in other assays.
    Full-length hPARP1
    Aufreinigung
    Affinity chromatography
    Reinheit
    > 95 %
  • Applikationshinweise
    10 ng/reaction
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconsitute in dH2O
    Lagerung
    -20 °C
  • Cinque, Ferino, Pedersen, Xodo: "Role of Poly [ADP-ribose] Polymerase 1 in Activating the Kirstenras (KRAS) Gene in Response to Oxidative Stress." in: International journal of molecular sciences, Vol. 21, Issue 17, (2020) (PubMed).

    Zhang, Wang, Ding, Yu: "Site-specific characterization of the Asp- and Glu-ADP-ribosylated proteome." in: Nature methods, Vol. 10, Issue 10, pp. 981-4, (2013) (PubMed).

  • Target
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Andere Bezeichnung
    Poly ADP ribose Polymerase 1 (PARP1 Produkte)
    Hintergrund
    Poly (ADP-ribose) polymerase-1 (PARP1) is an abundant and ubiquitous nuclear enzyme that catalyzes the NAD(+)-dependent addition of ADP-ribose polymers on a variety of nuclear proteins.
    Molekulargewicht
    113 kDa
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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