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Free PSA Protein

fPSA Spezies: Human Wirt: Human Native > 90 % by SDS-PAGE
Produktnummer ABIN1880349
  • Target Alle Free PSA (fPSA) Produkte
    Free PSA (fPSA) (Free Prostate Specific Antigen (fPSA))
    Protein-Typ
    Native
    Spezies
    Human
    Quelle
    • 1
    Human
    Aufreinigung
    Purified
    Reinheit
    > 90 % by SDS-PAGE
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    0.01 M PBS (pH 7.4 +/- 0.2)
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C
  • Target
    Free PSA (fPSA) (Free Prostate Specific Antigen (fPSA))
    Andere Bezeichnung
    Free PSA (fPSA Produkte)
    Hintergrund
    Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is an androgen-regulated serine protease produced by both prostate epithelial cells and prostate cancer (PCa) and is the most commonly used serum marker for cancer. It is a member of the tissue kallikrein family, some of the members of which are also prostate specific. PSA is a major protein in semen, where its function is to cleave semenogelins in the seminal coagulum. PSA is secreted into prostatic ducts as an inactive 244-amino acid proenzyme (proPSA) that is activated by cleavage of seven N-terminal amino acids. Measurement of free versus total PSA can increase specificity for PCa. PSA is also widely used to monitor responses to therapy and is under investigation as a therapeutic target.
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