EIF4E Protein (AA 1-217)

Produktnummer ABIN1945364

Dieses Recombinant EIF4E-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für EIF4E Protein (AA 1-217) (ABIN1945364)

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 1-217

Verwendungszweck: Recombinant Human Eukaryotic Translation Initiation Factor 4E/EIF4E

Sequenz: MATVEPETTP TPNPPTTEEE KTESNQEVAN PEHYIKHPLQ NRWALWFFKN DKSKTWQANL RLISKFDTVE DFWALYNHIQ LSSNLMPGCD YSLFKDGIEP MWEDEKNKRG GRWLITLNKQ QRRSDLDRFW LETLLCLIGE SFDDYSDDVC GAVVNVRAKG DKIAIWTTEC ENREAVTHIG RVYKERLGLP PKIVIGYQSH ADTATKSGST TKNRFVV

Produktmerkmale: Recombinant Human Eukaryotic Translation Initiation Factor 4E is produced by our E.coli expression system and the target gene encoding Met1-Val217 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 weeks

Antigendetails

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Andere Bezeichnung: Eukaryotic Translation Initiation Factor 4E

Hintergrund: Alternative Names: Eukaryotic translation initiation factor 4E,eIF-4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein,EIF4E,EIF4EL1,EIF4FEukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Molekulargewicht: 25.1 kDa

UniProt: P06730

Pathways: BCR Signaling