CCL6 Protein

Produktnummer ABIN2017707

Produktdetails

Target: CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Sequenz: GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA

Produktmerkmale: Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR1 transfected murine BaF3 cells is in a concentration range of 10-100 ng/mL.

Reinheit: > 97 % by SDS-PAGE and HPLC analyses.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1 EU/μg of rMuC10/CCL6 as determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Buffer: Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris, pH 8.0, 500 mM NaCl.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.

Antigendetails

Target: CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))

Andere Bezeichnung: C10/CCL6 (CCL6 Produkte)

Synonyme: MRP-1 Protein, Scya6 Protein, c10 Protein, Abcc1a Protein, Avcc1a Protein, Mrp Protein, Mrp1 Protein, Mrp-1 Protein, Scay6 Protein, chemokine (C-C motif) ligand 6 Protein, ATP binding cassette subfamily C member 1 Protein, Ccl6 Protein, Abcc1 Protein

Hintergrund: Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. Murine C10 is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines.
Synonyms: CCL6, MRP-1

Molekulargewicht: 10.7 kDa, a single non-glycosylated polypeptide chain containing 95 amino acids.